Strain SummaryC57BL/6-Apctm1Rak/+ Cbfa2t2tm1Swh/+

Strain Name

C57BL/6-Apctm1Rak/+ Cbfa2t2tm1Swh/+

Strain Type(s)

targeted mutation (knockout)

Strain Synonym(s)

Apc1638/+;Mtgr1+/−  •  Apc+/- Mtg16+/+ Mtgr1-/-

Description

Heterozygous Apc, Cbfa2t2 mutant mice on a predominantly C57BL/6 background with contribution from 129S6/SvEvTac and 129P2/OlaHsd from the original ES cells.

Strain Genetics

Apctm1Rak / Apc+
Cbfa2t2tm1Swh / Cbfa2t2+

Models

10 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon

observed

References: Parang B, Oncogene 2016 Dec 08;35(49):6341-6349

Intestine - Small Intestine - Distal tumor Intestine - Small Intestine - Distal

observed

References: Parang B, Oncogene 2016 Dec 08;35(49):6341-6349

Intestine - Small Intestine - Medial tumor Intestine - Small Intestine - Medial

observed

References: Parang B, Oncogene 2016 Dec 08;35(49):6341-6349

Intestine - Small Intestine - Proximal tumor Intestine - Small Intestine - Proximal

observed

References: Parang B, Oncogene 2016 Dec 08;35(49):6341-6349

Intestine - Small Intestine tumor Intestine - Small Intestine

95

References: Parang B, Oncogene 2016 Dec 08;35(49):6341-6349

Intestine adenocarcinoma Intestine

0

References: Parang B, Oncogene 2016 Dec 08;35(49):6341-6349

Intestine dysplasia - high grade Intestine

observed - 29

References: Parang B, Oncogene 2016 Dec 08;35(49):6341-6349

Intestine dysplasia - low grade Intestine

71

References: Parang B, Oncogene 2016 Dec 08;35(49):6341-6349

Intestine polyp Intestine

100

References: Parang B, Oncogene 2016 Dec 08;35(49):6341-6349

Intestine tumor Intestine

observed

References: Parang B, Oncogene 2016 Dec 08;35(49):6341-6349