Strain SummaryB6;129-Men1tm1.2Zqw Tg(Ins2-cre)23Herr

Strain Name

B6;129-Men1tm1.2Zqw Tg(Ins2-cre)23Herr

Strain Type(s)

targeted mutation (conditional)  •  transgenic

Strain Synonym(s)

BMen1  •  Men1F/F

Description

Homozygous Men1 mice also carrying the Tg(Ins2-cre)23Herr transgene on a mixed "129/Sv" (substrain unspecified) and C57BL/6 background with possible contribution from 129S4/SvJae, 129P2/OlaHsd, C57BL/6J, and/or CBA/J.

Strain Genetics

Tg(Ins2-cre)23Herr

Models

7 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Pancreas - Islet of Langerhans - Alpha cell glucagonoma Pancreas - Islet of Langerhans - Alpha cell

observed

References: Ripoche D, Mol Cell Biol 2015 Dec 28;36(5):756-64

Pancreas - Islet of Langerhans - Beta cell adenoma Pancreas - Islet of Langerhans - Beta cell

observed

References: Ripoche D, Mol Cell Biol 2015 Dec 28;36(5):756-64

Pancreas - Islet of Langerhans - Beta cell insulinoma Pancreas - Islet of Langerhans - Beta cell

observed

References: Ripoche D, Mol Cell Biol 2015 Dec 28;36(5):756-64

Pancreas - Islet of Langerhans - Beta cell lesion Pancreas - Islet of Langerhans - Beta cell

observed

References: Ripoche D, Mol Cell Biol 2015 Dec 28;36(5):756-64

Pancreas - Islet of Langerhans - Beta cell lesion - dysplastic Pancreas - Islet of Langerhans - Beta cell

observed

References: Ripoche D, Mol Cell Biol 2015 Dec 28;36(5):756-64

Pancreas - Islet of Langerhans - Beta cell tumor Pancreas - Islet of Langerhans - Beta cell

observed

References: Ripoche D, Mol Cell Biol 2015 Dec 28;36(5):756-64

Pancreas - Islet of Langerhans hyperplasia Pancreas - Islet of Langerhans

observed

References: Ripoche D, Mol Cell Biol 2015 Dec 28;36(5):756-64