Strain SummarySTOCK Ptentm2Mak Tg(MMTV-cre)#Tfln

Strain Name

STOCK Ptentm2Mak Tg(MMTV-cre)#Tfln

Strain Type(s)

targeted mutation (conditional)  •  transgenic

Strain Synonym(s)

MMTV-Cre:Ptenf/f  •  PtenΔf

Description

Compound mutant mice. The genetic background of these mice was stated to be mixed (FVB, C57BL/6, and "129/Sv" (substrain not specified)). It also contained at least some 129P2/OlaHsd and possibly some other strain(s).

Strain Genetics

Tg(MMTV-cre)#Tfln

Models

5 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Mammary gland adenocarcinoma - poorly differentiated Mammary gland

observed

References: Liu JC, EMBO Mol Med 2014 Dec;6(12):1542-60

Mammary gland adenocarcinoma - squamous Mammary gland

observed

References: Liu JC, EMBO Mol Med 2014 Dec;6(12):1542-60

Mammary gland adenomyoepithelioma Mammary gland

observed

References: Liu JC, EMBO Mol Med 2014 Dec;6(12):1542-60

Mammary gland carcinoma - sarcomatoid Mammary gland

observed

References: Liu JC, EMBO Mol Med 2014 Dec;6(12):1542-60

Mammary gland tumor Mammary gland

50 - 82

References: Liu JC, EMBO Mol Med 2014 Dec;6(12):1542-60