Strain Summary[not specified]-Ptch1tm1Bjw/+ Tg(Atoh1-cre/Esr1*)14Fsh

Strain Name

[not specified]-Ptch1tm1Bjw/+ Tg(Atoh1-cre/Esr1*)14Fsh

Strain Type(s)

targeted mutation (conditional)  •  transgenic

Strain Synonym(s)

Math1-creERT2:Ptc+/-  •  Ptc+/-

Description

Heterozygous Ptch1tm1Bjw mice also carrying the Tg(Atoh1-cre/Esr1*)14Fsh on an unspecified background with possible contribution from 129T2/SvEms and 129S6/SvEvTac.

Strain Genetics

Tg(Atoh1-cre/Esr1*)14Fsh
Tg(Atoh1-cre/Esr1*)14Fsh
Tg(Atoh1-cre/Esr1*)14Fsh
Ptch1tm1Bjw / Ptch1+

Models

3 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
CNS - Brain - Cerebellum medulloblastoma CNS - Brain - Cerebellum tamoxifen (For inducing expression from mutant alleles)

observed

References: Schuller U, Cancer Cell 2008 Aug 12;14(2):123-34

CNS - Brain - Cerebellum normal tissue (control) CNS - Brain - Cerebellum tamoxifen (For inducing expression from mutant alleles)

not applicable

References: Schuller U, Cancer Cell 2008 Aug 12;14(2):123-34

CNS - Brain tumor CNS - Brain tamoxifen (For inducing expression from mutant alleles)

observed

References: Schuller U, Cancer Cell 2008 Aug 12;14(2):123-34