Strain Summary[not specified]-Men1tm1.2Zqw Tg(Ins2-cre)23Herr

Strain Name

[not specified]-Men1tm1.2Zqw Tg(Ins2-cre)23Herr

Strain Type(s)

targeted mutation (conditional)  •  transgenic

Strain Synonym(s)

Men1F/F-RipCre+

Description

Homozygous floxed mice carrying a cre-expressing transgene. The genetic background of these mice was not specified but included at least some 129P2/OlaHsd, likely C57BL/6J and CBA/J, and possibly some DBA/2.

Strain Genetics

Tg(Ins2-cre)23Herr

Models

4 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Pancreas - Islet of Langerhans - Beta cell carcinoma Pancreas - Islet of Langerhans - Beta cell

100

References: Bertolino P, Cancer Res 2003 Aug 15;63(16):4836-41

Pancreas - Islet of Langerhans - Beta cell hyperplasia Pancreas - Islet of Langerhans - Beta cell

27

References: Bertolino P, Cancer Res 2003 Aug 15;63(16):4836-41

Pancreas - Islet of Langerhans - Beta cell insulinoma Pancreas - Islet of Langerhans - Beta cell

42 - 100

References: Bertolino P, Cancer Res 2003 Aug 15;63(16):4836-41

Pancreas - Islet of Langerhans - Beta cell preneoplastic lesion Pancreas - Islet of Langerhans - Beta cell

87.5 - 100

References: Bertolino P, Cancer Res 2003 Aug 15;63(16):4836-41