Strain SummaryB6;129-Men1tm1Rvt/+

Strain Name

B6;129-Men1tm1Rvt/+

Strain Type(s)

targeted mutation (knockout)

Strain Synonym(s)

Men1+/-

Description

Heterozygous mice. The genetic background of these mice was a mixture of C57BL/6, 129S6/SvEv, and possibly some other 129 substrain(s).

Strain Genetics

Men1tm1Rvt / Men1+

Models

48 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Adipose tissue lipoma Adipose tissue

observed

References: Harding B, Endocr Relat Cancer 2009 Dec;16(4):1313-27

Adrenal gland - Cortex adenoma Adrenal gland - Cortex

observed

References: Harding B, Endocr Relat Cancer 2009 Dec;16(4):1313-27

Adrenal gland - Cortex hyperplasia Adrenal gland - Cortex

observed

References: Harding B, Endocr Relat Cancer 2009 Dec;16(4):1313-27

Adrenal gland - Cortex tumor Adrenal gland - Cortex

0

16

10

References: Harding B, Endocr Relat Cancer 2009 Dec;16(4):1313-27

Adrenal gland - Medulla pheochromocytoma Adrenal gland - Medulla

observed

References: Harding B, Endocr Relat Cancer 2009 Dec;16(4):1313-27

Adrenal gland - Subcapsular cell hyperplasia Adrenal gland - Subcapsular cell

observed

References: Harding B, Endocr Relat Cancer 2009 Dec;16(4):1313-27

Adrenal gland adenoma Adrenal gland

observed

References: Harding B, Endocr Relat Cancer 2009 Dec;16(4):1313-27

Adrenal gland tumor Adrenal gland

observed

References: Harding B, Endocr Relat Cancer 2009 Dec;16(4):1313-27

Intestine - Small Intestine - Duodenum - Proximal tumor - neuroendocrine Intestine - Small Intestine - Duodenum - Proximal

0

References: Harding B, Endocr Relat Cancer 2009 Dec;16(4):1313-27

Ovary - Germ cell dysgerminoma Ovary - Germ cell

observed

References: Harding B, Endocr Relat Cancer 2009 Dec;16(4):1313-27

Ovary - Granulosa cell tumor Ovary - Granulosa cell

observed

References: Harding B, Endocr Relat Cancer 2009 Dec;16(4):1313-27

Ovary - Sex cord stromal cell tumor Ovary - Sex cord stromal cell

observed

References: Harding B, Endocr Relat Cancer 2009 Dec;16(4):1313-27

Ovary luteoma Ovary

observed

References: Harding B, Endocr Relat Cancer 2009 Dec;16(4):1313-27

Ovary tumor Ovary

40

References: Harding B, Endocr Relat Cancer 2009 Dec;16(4):1313-27

Ovary tumor - tubulostromal Ovary

observed

References: Harding B, Endocr Relat Cancer 2009 Dec;16(4):1313-27

Pancreas - Islet of Langerhans - Beta cell insulinoma Pancreas - Islet of Langerhans - Beta cell

observed

References: Harding B, Endocr Relat Cancer 2009 Dec;16(4):1313-27

Pancreas - Islet of Langerhans adenoma Pancreas - Islet of Langerhans

60%

References: Harding B, Endocr Relat Cancer 2009 Dec;16(4):1313-27

Pancreas - Islet of Langerhans gastrinoma Pancreas - Islet of Langerhans

0

References: Harding B, Endocr Relat Cancer 2009 Dec;16(4):1313-27

Pancreas - Islet of Langerhans hyperplasia Pancreas - Islet of Langerhans

observed

References: Harding B, Endocr Relat Cancer 2009 Dec;16(4):1313-27

Pancreas - Islet of Langerhans neoplasia Pancreas - Islet of Langerhans

observed

References: Harding B, Endocr Relat Cancer 2009 Dec;16(4):1313-27

Pancreas - Islet of Langerhans tumor Pancreas - Islet of Langerhans

57

45

60%

References: Harding B, Endocr Relat Cancer 2009 Dec;16(4):1313-27

Parathyroid gland adenoma Parathyroid gland

25

26

25

References: Harding B, Endocr Relat Cancer 2009 Dec;16(4):1313-27

Parathyroid gland adenoma - papillary Parathyroid gland

observed

References: Harding B, Endocr Relat Cancer 2009 Dec;16(4):1313-27

Parathyroid gland hyperplasia - focal Parathyroid gland

60

References: Harding B, Endocr Relat Cancer 2009 Dec;16(4):1313-27

Parathyroid gland hyperplasia - nodular Parathyroid gland

observed

References: Harding B, Endocr Relat Cancer 2009 Dec;16(4):1313-27

Parathyroid gland lesion Parathyroid gland

85

References: Harding B, Endocr Relat Cancer 2009 Dec;16(4):1313-27

Parathyroid gland tumor Parathyroid gland

40 - 85

References: Harding B, Endocr Relat Cancer 2009 Dec;16(4):1313-27

Pituitary gland - Anterior adenoma - macroadenoma Pituitary gland - Anterior

observed

References: Harding B, Endocr Relat Cancer 2009 Dec;16(4):1313-27

Pituitary gland - Anterior prolactinoma Pituitary gland - Anterior

observed

References: Harding B, Endocr Relat Cancer 2009 Dec;16(4):1313-27

Pituitary gland - Anterior somatolactotrophinoma Pituitary gland - Anterior

observed

References: Harding B, Endocr Relat Cancer 2009 Dec;16(4):1313-27

Pituitary gland - Anterior tumor Pituitary gland - Anterior

35

References: Harding B, Endocr Relat Cancer 2009 Dec;16(4):1313-27

Pituitary gland - Pars distalis tumor Pituitary gland - Pars distalis

observed

References: Harding B, Endocr Relat Cancer 2009 Dec;16(4):1313-27

Pituitary gland - Pars intermedia tumor Pituitary gland - Pars intermedia

observed

References: Harding B, Endocr Relat Cancer 2009 Dec;16(4):1313-27

Pituitary gland - Pars nervosa tumor Pituitary gland - Pars nervosa

0

References: Harding B, Endocr Relat Cancer 2009 Dec;16(4):1313-27

Pituitary gland adenoma Pituitary gland

observed

References: Harding B, Endocr Relat Cancer 2009 Dec;16(4):1313-27

Pituitary gland adenoma - macroadenoma Pituitary gland

observed

References: Harding B, Endocr Relat Cancer 2009 Dec;16(4):1313-27

Pituitary gland hyperplasia - focal Pituitary gland

observed

References: Harding B, Endocr Relat Cancer 2009 Dec;16(4):1313-27

Pituitary gland tumor Pituitary gland

43

3.9

References: Harding B, Endocr Relat Cancer 2009 Dec;16(4):1313-27

Stomach tumor - neuroendocrine Stomach

0

References: Harding B, Endocr Relat Cancer 2009 Dec;16(4):1313-27

Testis - Leydig cell (Interstitial cell) hyperplasia Testis - Leydig cell (Interstitial cell)

45

References: Harding B, Endocr Relat Cancer 2009 Dec;16(4):1313-27

Testis - Leydig cell (Interstitial cell) tumor Testis - Leydig cell (Interstitial cell)

60

References: Harding B, Endocr Relat Cancer 2009 Dec;16(4):1313-27

Testis - Leydig cell (Interstitial cell) tumor - malignant Testis - Leydig cell (Interstitial cell)

observed

References: Harding B, Endocr Relat Cancer 2009 Dec;16(4):1313-27

Testis teratoma Testis

1.3

References: Harding B, Endocr Relat Cancer 2009 Dec;16(4):1313-27

Testis tumor Testis

65

References: Harding B, Endocr Relat Cancer 2009 Dec;16(4):1313-27

Thyroid gland - Follicular cell adenoma Thyroid gland - Follicular cell

10

References: Harding B, Endocr Relat Cancer 2009 Dec;16(4):1313-27

Thyroid gland - Medulla - C cell adenoma Thyroid gland - Medulla - C cell

5

References: Harding B, Endocr Relat Cancer 2009 Dec;16(4):1313-27

Thyroid gland adenoma Thyroid gland

15

References: Harding B, Endocr Relat Cancer 2009 Dec;16(4):1313-27

(Unspecified organ) tumor (Unspecified organ)

47

48

5 - 84

References: Harding B, Endocr Relat Cancer 2009 Dec;16(4):1313-27