Strain SummaryC57BL/6-Ctnnb1tm2Kem Men1tm1.2Zqw Tg(Ins2-cre)23Herr

Strain Name

C57BL/6-Ctnnb1tm2Kem Men1tm1.2Zqw Tg(Ins2-cre)23Herr

Strain Type(s)

targeted mutation (conditional)  •  transgenic

Strain Synonym(s)

BMen1/Bcat-KO

Description

Homozygous Ctnnb1, Men1 mutant mice also carrying the Tg(Ins2-cre)23Herr transgene on a predominantly C57BL/6J background with possible contribution from 129X1/SvJ, 129S1/SvJ, 129P2/OlaHsd, and/or CBA/J.

Strain Genetics

Tg(Ins2-cre)23Herr

Models

6 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Pancreas - Islet of Langerhans - Beta cell insulinoma Pancreas - Islet of Langerhans - Beta cell

observed - 33

References: Jiang X, Nat Commun 2014;5():5809

Pancreas - Islet of Langerhans hyperplasia Pancreas - Islet of Langerhans

observed

References: Jiang X, Nat Commun 2014;5():5809

Pancreas - Islet of Langerhans tumor Pancreas - Islet of Langerhans

observed

References: Jiang X, Nat Commun 2014;5():5809

Pancreas tumor Pancreas

observed - high

References: Jiang X, Nat Commun 2014;5():5809

Pancreas tumor - malignant Pancreas

0

References: Jiang X, Nat Commun 2014;5():5809

Pancreas tumor - neuroendocrine Pancreas

observed

References: Jiang X, Nat Commun 2014;5():5809