Strain SummaryFVB;129P3-Erbb2tm8(Erbb2)Mul/+ Ptentm1Hwu/+ Tg(MMTV-cre)7Mul

Strain Name

FVB;129P3-Erbb2tm8(Erbb2)Mul/+ Ptentm1Hwu/+ Tg(MMTV-cre)7Mul

Strain Type(s)

targeted mutation (conditional)  •  transgenic

Strain Synonym(s)

129:FVB/N-Erbb2tm8(Erbb2)Mul/+ Ptentm1Hwu/+ Tg(MMTV-cre)7Mul  •  FVB;129-Erbb2tm8(Erbb2)Mul/+ Ptentm1Hwu/+ Tg(MMTV-cre)7Mul  •  PTEN+/-/ErbB-2KI  •  PTEN+/-/NeuNT

Description

Heterozygous Ptentm1Hwu, Erbb2tm8(Erbb2)Mul mice carrying the Tg(MMTV-cre)7Mul transgene on a mixed 129P3/J and FVB/N genetic background with possible contribution from 129X1/SvJ, 129S1/Sv, and/or 129S4/SvJae.

Strain Genetics

Tg(MMTV-cre)7Mul
Ptentm1Hwu / Pten+
Erbb2tm8(Erbb2)Mul / Erbb2+

Models

2 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Leukocyte lymphoma Leukocyte

observed

References: Dourdin N, Cancer Res 2008 Apr 1;68(7):2122-31

Mammary gland tumor Mammary gland

100

References: Dourdin N, Cancer Res 2008 Apr 1;68(7):2122-31

Sites of Metastasis: Lung