Mouse Tumor Biology Database (MTB)
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Last Database Update
2019-12-01
MTB 3.0
 
HelpHelp and Documentation Strain Tumor Overview
Collapsed View
 
Strain
B6;129-Trp53tm1Brd
Strain Synonyms p53-knockout  •  p53-/-
Strain Note: Homozygous Trp53tm1Brd mice on a mixed C57BL/6 (~94%) and 129/Sv (~6%) background with possible contribution from 129S7/SvEvBrd-Hprt+.
Strain Tumor Overview Expanded View
Tumors 81 unique tumor types displayed.

A tumor group is a set of tumors that share the same tumor name, organ(s) affected, and treatment type.

Tumor Name Organ(s) Affected Treatment Type Number of
Tumor Group Records
Frequency Range
Adrenal gland - Medulla pheochromocytoma Adrenal gland - Medulla Diet 1 3.57
Blood vessel hemangiosarcoma Blood vessel Diet 7 0 - 17.86
Blood vessel hemangiosarcoma Muscle Diet 2 6.67 - 7.14
Blood vessel hemangiosarcoma Lung Diet 2 3.57 - 6.67
Blood vessel hemangiosarcoma Subcutis Diet 1 3.33
Blood vessel hemangiosarcoma Lymph node Diet 1 3.33
Blood vessel hemangiosarcoma Liver Diet 1 3.57
Blood vessel hemangiosarcoma Spleen Diet 1 3.57
Blood vessel hemangiosarcoma Blood vessel Hormone 1 25
Blood vessel hemangiosarcoma Blood vessel Chemical/Drug 2 10.71 - 25
Bone osteosarcoma Bone Diet 3 0 - observed
CNS - Brain - Astrocyte astrocytoma CNS - Brain - Astrocyte Diet 1 3.33
Intestine - Large Intestine - Cecum adenoma Intestine - Large Intestine - Cecum Diet 4 0 - 3.33
Kidney carcinoma Kidney Diet 1 3.57
Leukocyte - Lymphoblast lymphoma Leukocyte - Lymphoblast Diet 1 25
Leukocyte - Lymphoblast lymphoma - lymphoblastic Leukocyte - Lymphoblast Diet 7 observed - 48.15
Leukocyte - Lymphoblast lymphoma - lymphoblastic Leukocyte - Lymphoblast Hormone 1 7.14
Leukocyte - Lymphoblast lymphoma - lymphoblastic Leukocyte - Lymphoblast Chemical/Drug 1 32.14
Leukocyte - Lymphocyte - B-lymphocyte - Follicular center cell lymphoma - follicular Leukocyte - Lymphocyte - B-lymphocyte - Follicular center cell Diet 9 observed
Leukocyte - Lymphocyte - B-lymphocyte - Follicular center cell lymphoma - follicular Leukocyte - Lymphocyte - B-lymphocyte - Follicular center cell Chemical/Drug 1 observed
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Leukocyte - Monocyte - Macrophage - Histiocyte Diet 6 3.33 - 36.67
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Leukocyte - Monocyte - Macrophage - Histiocyte Hormone 1 10.71
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Leukocyte - Monocyte - Macrophage - Histiocyte Chemical/Drug 2 0 - 7.14
Leukocyte - Myelocyte (Granulocyte) - Basophil - Mast cell tumor Leukocyte - Myelocyte (Granulocyte) - Basophil - Mast cell Diet 4 0 - 3.57
Leukocyte - Myelocyte (Granulocyte) - Basophil - Mast cell tumor Leukocyte - Myelocyte (Granulocyte) - Basophil - Mast cell Chemical/Drug 1 0
Leukocyte - Myelocyte (Granulocyte) leukemia Leukocyte - Myelocyte (Granulocyte) Diet 1 3.57
Leukocyte - Myelocyte (Granulocyte) leukemia - myelocytic Leukocyte - Myelocyte (Granulocyte) Diet 2 3.33 - 3.57
Leukocyte lymphoma Leukocyte Diet 15 13.33 - 78.57
Leukocyte lymphoma Thymus Diet 5 observed - 3.33
Leukocyte lymphoma Spleen Diet 1 3.33
Leukocyte lymphoma Leukocyte Chemical/Drug 2 53.57 - 64.29
Leukocyte lymphoma Thymus Chemical/Drug 1 observed
Leukocyte lymphoma - immunoblastic Leukocyte Diet 8 observed
Leukocyte lymphoma - immunoblastic Leukocyte Hormone 1 observed
Leukocyte lymphoma - immunoblastic Thymus Chemical/Drug 1 observed
Leukocyte lymphoma - pleomorphic Leukocyte Diet 9 0 - 20
Leukocyte lymphoma - pleomorphic Thymus Diet 1 observed
Leukocyte tumor Leukocyte Diet 1 25
Liver carcinoma Liver Diet 1 3.33
Liver hepatoblastoma Liver Diet 3 0 - observed
Liver hepatocellular adenoma Liver Diet 3 0 - 3.33
Liver hepatocellular carcinoma Liver Diet 3 0 - observed
Liver hepatocholangiocarcinoma Liver Diet 6 0 - observed
Liver hepatocholangiocarcinoma Liver Hormone 1 observed
Liver hepatocholangiocarcinoma Liver Chemical/Drug 1 observed
Liver neoplasm Liver Diet 3 0 - 6.67
Liver tumor - benign Liver Diet 3 0
Lung - Alveolus adenoma - alveolar Lung - Alveolus Diet 2 0
Lung - Alveolus carcinoma Lung - Alveolus Diet 1 6.67
Lung - Alveolus neoplasm - malignant Lung - Alveolus Diet 1 3.33
Lymph node carcinoma Lymph node Diet 1 3.33
Mesodermal cell/mesoblast sarcoma Mesodermal cell/mesoblast Diet 8 6.67 - 43.33
Mesodermal cell/mesoblast sarcoma Leg Diet 2 3.57 - 6.67
Mesodermal cell/mesoblast sarcoma Prostate gland Diet 1 3.33
Mesodermal cell/mesoblast sarcoma Body wall Diet 1 3.57
Mesodermal cell/mesoblast sarcoma Lymph node Diet 1 3.57
Mesodermal cell/mesoblast sarcoma - anaplastic Mesodermal cell/mesoblast Diet 2 observed
Muscle - Smooth leiomyosarcoma Stomach Diet 1 3.33
Neuroblast neuroblastoma Neuroblast Diet 1 6.67
Neuroblast neuroblastoma Nose Diet 1 3.33
Neuroblast neuroblastoma CNS - Spinal cord Diet 1 3.33
Neuroblast neuroblastoma Nose - Nasal cavity Diet 1 3.57
Nose - Nasal cavity carcinoma Nose - Nasal cavity Diet 1 3.57
Stomach squamous cell papilloma Stomach Diet 1 3.33
Testis - Leydig cell (Interstitial cell) tumor Testis - Leydig cell (Interstitial cell) Diet 4 observed
Testis - Leydig cell (Interstitial cell) tumor Testis - Leydig cell (Interstitial cell) Hormone 1 observed
Thymus thymoma Thymus Diet 5 0 - 13.33
Tooth odontoma Tooth Diet 3 0 - 3.33
(Unspecified organ) carcinoma (Unspecified organ) Diet 2 7.14 - 13.33
(Unspecified organ) neoplasia (Unspecified organ) Diet 3 85.71 - 100
(Unspecified organ) neoplasia (Unspecified organ) Chemical/Drug 2 85.71 - 100
(Unspecified organ) neoplasm (Unspecified organ) Diet 1 20
(Unspecified organ) neoplasm - benign (Unspecified organ) Diet 3 10.71 - 20
(Unspecified organ) neoplasm - malignant (Unspecified organ) Diet 11 7.14 - 86.67
(Unspecified organ) squamous cell papilloma (Unspecified organ) Diet 3 0 - 3.33
(Unspecified organ) tumor (Unspecified organ) Diet 18 observed - 100
(Unspecified organ) tumor (Unspecified organ) Hormone 2 39.29 - 85.71
(Unspecified organ) tumor (Unspecified organ) Chemical/Drug 2 60.71 - 64.29
(Unspecified organ) tumor - non-hematopoietic (Unspecified organ) Diet 3 10.71 - 25
(Unspecified organ) tumor - non-hematopoietic (Unspecified organ) Hormone 1 46.43
(Unspecified organ) tumor - non-hematopoietic (Unspecified organ) Chemical/Drug 1 35.71