Strain Summary[not specified]-Gt(ROSA)26Sortm1(EYFP)Cos Ptentm2Mak Rb1tm2Brn Trp53tm1Brn

Strain Name

[not specified]-Gt(ROSA)26Sortm1(EYFP)Cos Ptentm2Mak Rb1tm2Brn Trp53tm1Brn

Strain Type(s)

targeted mutation (conditional)  •  targeted mutation (knock-in)

Strain Synonym(s)

Tp53flx/flx; Rbflx/flx; Ptenflx/flx; ROSAYFP

Description

Compound mutant mice on an unspecified genetic background with possible contribution from 129X1/SvJ, 129P2/OlaHsd, and 129.

Strain Genetics

Gt(ROSA)26Sortm1(EYFP)Cos

Models

46 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
CNS - Brain - Choroid plexus carcinoma CNS - Brain - Choroid plexus Plasmid pcDNA3.1 expressing Cre-Recombinase and GFP

observed - 37.68

References: Tong Y, Cancer Cell 2015 May 11;27(5):712-27

CNS - Brain - Choroid plexus carcinoma CNS - Brain - Choroid plexus Plasmid pcDNA3.1 expressing Cre-Recombinase and GFP   ⋅   lentivirus expressing Taf12 shRNA and GFP

0

References: Tong Y, Cancer Cell 2015 May 11;27(5):712-27

CNS - Brain - Choroid plexus carcinoma CNS - Brain - Choroid plexus Plasmid pcDNA3.1 expressing Cre-Recombinase and GFP   ⋅   lentivirus expressing Nyyc shRNA and GFP

0

References: Tong Y, Cancer Cell 2015 May 11;27(5):712-27

CNS - Brain - Choroid plexus carcinoma CNS - Brain - Choroid plexus Plasmid pcDNA3.1 expressing Cre-Recombinase and GFP   ⋅   lentivirus expressing Rad54l shRNA and GFP

10

References: Tong Y, Cancer Cell 2015 May 11;27(5):712-27

CNS - Brain - Choroid plexus carcinoma CNS - Brain - Choroid plexus Plasmid pcDNA3.1 expressing Cre-Recombinase and GFP   ⋅   lentivirus expressing control shRNA and GFP

41.67

References: Tong Y, Cancer Cell 2015 May 11;27(5):712-27

CNS - Brain - Choroid plexus carcinoma CNS - Brain - Choroid plexus Plasmid pcDNA3.1 expressing Cre-Recombinase and GFP   ⋅   lentivirus expressing Rad54l and GFP   ⋅   lentivirus expressing Nfyc and GFP   ⋅   lentivirus expressing Taf12 and GFP

observed

References: Tong Y, Cancer Cell 2015 May 11;27(5):712-27

CNS - Brain - Choroid plexus carcinoma CNS - Brain - Choroid plexus lentivirus expressing Rad54l and GFP   ⋅   Plasmid control pcDNA3.1 and GFP   ⋅   lentivirus expressing Nfyc and GFP   ⋅   lentivirus expressing Taf12 and GFP

0

References: Tong Y, Cancer Cell 2015 May 11;27(5):712-27

CNS - Brain - Choroid plexus carcinoma CNS - Brain - Choroid plexus lentivirus expressing Cre-recombinase and GFP

0 - 85.71

References: Tong Y, Cancer Cell 2015 May 11;27(5):712-27

CNS - Brain - Choroid plexus carcinoma CNS - Brain - Choroid plexus lentivirus expressing Cre-recombinase and GFP   ⋅   lentivirus expressing Taf12 and GFP

22.22

References: Tong Y, Cancer Cell 2015 May 11;27(5):712-27

CNS - Brain - Choroid plexus carcinoma CNS - Brain - Choroid plexus lentivirus expressing Rad54l and GFP   ⋅   lentivirus expressing Cre-recombinase and GFP   ⋅   lentivirus expressing Nfyc and GFP   ⋅   lentivirus expressing Taf12 and GFP

50 - 75

References: Tong Y, Cancer Cell 2015 May 11;27(5):712-27

CNS - Brain - Choroid plexus dysplasia CNS - Brain - Choroid plexus Plasmid pcDNA3.1 expressing Cre-Recombinase and GFP   ⋅   Plasmid pcDNA3.1 expressing Taf12 and GFP

observed

References: Tong Y, Cancer Cell 2015 May 11;27(5):712-27

CNS - Brain - Choroid plexus dysplasia CNS - Brain - Choroid plexus Plasmid pcDNA3.1 expressing Cre-Recombinase and GFP   ⋅   Plasmid pcDNA3.1 expressing Nfyc and GFP

observed

References: Tong Y, Cancer Cell 2015 May 11;27(5):712-27

CNS - Brain - Choroid plexus dysplasia CNS - Brain - Choroid plexus Plasmid pcDNA3.1 expressing Cre-Recombinase and GFP   ⋅   Plasmid pcDNA3.1 expressing Rad54l and GFP

observed

References: Tong Y, Cancer Cell 2015 May 11;27(5):712-27

CNS - Brain - Choroid plexus dysplasia CNS - Brain - Choroid plexus Plasmid pcDNA3.1 expressing Cre-Recombinase and GFP   ⋅   Plasmid pcDNA3.1 expressing Cdc20 and GFP

0

References: Tong Y, Cancer Cell 2015 May 11;27(5):712-27

CNS - Brain - Choroid plexus dysplasia CNS - Brain - Choroid plexus Plasmid pcDNA3.1 expressing Cre-Recombinase and GFP   ⋅   Plasmid pcDNA3.1 expressing Stmn1 and GFP

0

References: Tong Y, Cancer Cell 2015 May 11;27(5):712-27

CNS - Brain - Choroid plexus dysplasia CNS - Brain - Choroid plexus Plasmid pcDNA3.1 expressing Cre-Recombinase and GFP   ⋅   Plasmid pcDNA3.1 expressing Atp6v0b and GFP

0

References: Tong Y, Cancer Cell 2015 May 11;27(5):712-27

CNS - Brain - Choroid plexus dysplasia CNS - Brain - Choroid plexus Plasmid pcDNA3.1 expressing Cre-Recombinase and GFP   ⋅   Plasmid pcDNA3.1 expressing Clspn and GFP

0

References: Tong Y, Cancer Cell 2015 May 11;27(5):712-27

CNS - Brain - Choroid plexus dysplasia CNS - Brain - Choroid plexus Plasmid pcDNA3.1 expressing Cre-Recombinase and GFP   ⋅   Plasmid pcDNA3.1 expressing Mier1 and GFP

0

References: Tong Y, Cancer Cell 2015 May 11;27(5):712-27

CNS - Brain - Choroid plexus dysplasia CNS - Brain - Choroid plexus Plasmid pcDNA3.1 expressing Cre-Recombinase and GFP   ⋅   Plasmid pcDNA3.1 expressing Dvl1 and GFP

0

References: Tong Y, Cancer Cell 2015 May 11;27(5):712-27

CNS - Brain - Choroid plexus dysplasia CNS - Brain - Choroid plexus Plasmid pcDNA3.1 expressing Cre-Recombinase and GFP   ⋅   Plasmid pcDNA3.1 expressing Pgd and GFP

0

References: Tong Y, Cancer Cell 2015 May 11;27(5):712-27

CNS - Brain - Choroid plexus dysplasia CNS - Brain - Choroid plexus Plasmid pcDNA3.1 expressing Cre-Recombinase and GFP   ⋅   Plasmid pcDNA3.1 expressing Gpatch3 and GFP

0

References: Tong Y, Cancer Cell 2015 May 11;27(5):712-27

CNS - Brain - Choroid plexus dysplasia CNS - Brain - Choroid plexus Plasmid pcDNA3.1 expressing Cre-Recombinase and GFP   ⋅   Plasmid pcDNA3.1 expressing Rpa2 and GFP

0

References: Tong Y, Cancer Cell 2015 May 11;27(5):712-27

CNS - Brain - Choroid plexus dysplasia CNS - Brain - Choroid plexus Plasmid pcDNA3.1 expressing Cre-Recombinase and GFP   ⋅   Plasmid pcDNA3.1 expressing Rragc and GFP

0

References: Tong Y, Cancer Cell 2015 May 11;27(5):712-27

CNS - Brain - Choroid plexus dysplasia CNS - Brain - Choroid plexus Plasmid pcDNA3.1 expressing Cre-Recombinase and GFP   ⋅   Plasmid pcDNA3.1 expressing Ctps and GFP

0

References: Tong Y, Cancer Cell 2015 May 11;27(5):712-27

CNS - Brain - Choroid plexus dysplasia CNS - Brain - Choroid plexus Plasmid pcDNA3.1 expressing Cre-Recombinase and GFP   ⋅   Plasmid pcDNA3.1 expressing Elovl1 and GFP

0

References: Tong Y, Cancer Cell 2015 May 11;27(5):712-27

CNS - Brain - Choroid plexus dysplasia CNS - Brain - Choroid plexus Plasmid pcDNA3.1 expressing Cre-Recombinase and GFP   ⋅   Plasmid pcDNA3.1 expressing Dph2 and GFP

0

References: Tong Y, Cancer Cell 2015 May 11;27(5):712-27

CNS - Brain - Choroid plexus dysplasia CNS - Brain - Choroid plexus Plasmid pcDNA3.1 expressing Cre-Recombinase and GFP   ⋅   Plasmid pcDNA3.1 expressing Toe1 and GFP

0

References: Tong Y, Cancer Cell 2015 May 11;27(5):712-27

CNS - Brain - Choroid plexus dysplasia CNS - Brain - Choroid plexus Plasmid pcDNA3.1 expressing Cre-Recombinase and GFP   ⋅   Plasmid pcDNA3.1 expressing Usp1 and GFP

0

References: Tong Y, Cancer Cell 2015 May 11;27(5):712-27

CNS - Brain - Choroid plexus dysplasia CNS - Brain - Choroid plexus Plasmid pcDNA3.1 expressing Cre-Recombinase and GFP   ⋅   Plasmid pcDNA3.1 expressing Kti12 and GFP

0

References: Tong Y, Cancer Cell 2015 May 11;27(5):712-27

CNS - Brain - Choroid plexus dysplasia CNS - Brain - Choroid plexus Plasmid pcDNA3.1 expressing Cre-Recombinase and GFP   ⋅   Plasmid pcDNA3.1 expressing Pqlc2 and GFP

0

References: Tong Y, Cancer Cell 2015 May 11;27(5):712-27

CNS - Brain - Choroid plexus dysplasia CNS - Brain - Choroid plexus Plasmid pcDNA3.1 expressing Cre-Recombinase and GFP   ⋅   Plasmid pcDNA3.1 expressing Kif2c and GFP

0

References: Tong Y, Cancer Cell 2015 May 11;27(5):712-27

CNS - Brain - Choroid plexus dysplasia CNS - Brain - Choroid plexus Plasmid pcDNA3.1 expressing Cre-Recombinase and GFP

observed

References: Tong Y, Cancer Cell 2015 May 11;27(5):712-27

CNS - Brain - Choroid plexus hyperplasia CNS - Brain - Choroid plexus Plasmid pcDNA3.1 expressing Cre-Recombinase and GFP

observed

References: Tong Y, Cancer Cell 2015 May 11;27(5):712-27

CNS - Brain - Choroid plexus hyperplasia CNS - Brain - Choroid plexus Plasmid pcDNA3.1 expressing Cre-Recombinase and GFP   ⋅   Plasmid pcDNA3.1 expressing Taf12 and GFP

observed

References: Tong Y, Cancer Cell 2015 May 11;27(5):712-27

CNS - Brain - Choroid plexus hyperplasia CNS - Brain - Choroid plexus Plasmid pcDNA3.1 expressing Cre-Recombinase and GFP   ⋅   Plasmid pcDNA3.1 expressing Nfyc and GFP

observed

References: Tong Y, Cancer Cell 2015 May 11;27(5):712-27

CNS - Brain - Choroid plexus hyperplasia CNS - Brain - Choroid plexus Plasmid pcDNA3.1 expressing Cre-Recombinase and GFP   ⋅   Plasmid pcDNA3.1 expressing Rad54l and GFP

observed

References: Tong Y, Cancer Cell 2015 May 11;27(5):712-27

CNS - Brain - Choroid plexus hyperplasia CNS - Brain - Choroid plexus Plasmid pcDNA3.1 expressing Cre-Recombinase and GFP   ⋅   Plasmid pcDNA3.1 expressing Cdc20 and GFP

0

References: Tong Y, Cancer Cell 2015 May 11;27(5):712-27

CNS - Brain - Choroid plexus hyperplasia CNS - Brain - Choroid plexus Plasmid pcDNA3.1 expressing Cre-Recombinase and GFP   ⋅   Plasmid pcDNA3.1 expressing Stmn1 and GFP

0

References: Tong Y, Cancer Cell 2015 May 11;27(5):712-27

CNS - Brain - Choroid plexus hyperplasia CNS - Brain - Choroid plexus Plasmid pcDNA3.1 expressing Cre-Recombinase and GFP   ⋅   Plasmid pcDNA3.1 expressing Atp6v0b and GFP

0

References: Tong Y, Cancer Cell 2015 May 11;27(5):712-27

CNS - Brain - Choroid plexus hyperplasia CNS - Brain - Choroid plexus Plasmid pcDNA3.1 expressing Cre-Recombinase and GFP   ⋅   Plasmid pcDNA3.1 expressing Clspn and GFP

0

References: Tong Y, Cancer Cell 2015 May 11;27(5):712-27

CNS - Brain - Choroid plexus hyperplasia CNS - Brain - Choroid plexus Plasmid pcDNA3.1 expressing Cre-Recombinase and GFP   ⋅   Plasmid pcDNA3.1 expressing Mier1 and GFP

0

References: Tong Y, Cancer Cell 2015 May 11;27(5):712-27

CNS - Brain - Choroid plexus hyperplasia CNS - Brain - Choroid plexus lentivirus expressing Cre-recombinase and GFP

observed

References: Tong Y, Cancer Cell 2015 May 11;27(5):712-27

CNS - Brain - Choroid plexus tumor CNS - Brain - Choroid plexus Plasmid pcDNA3.1 expressing Cre-Recombinase and GFP

observed - 44.93

References: Tong Y, Cancer Cell 2015 May 11;27(5):712-27

CNS - Brain - Choroid plexus tumor CNS - Brain - Choroid plexus Plasmid pcDNA3.1 expressing Cre-Recombinase and GFP   ⋅   lentivirus expressing Rad54l and GFP   ⋅   lentivirus expressing Nfyc and GFP   ⋅   lentivirus expressing Taf12 and GFP

52.78

References: Tong Y, Cancer Cell 2015 May 11;27(5):712-27

CNS - Brain - Choroid plexus tumor CNS - Brain - Choroid plexus lentivirus expressing Rad54l and GFP   ⋅   Plasmid control pcDNA3.1 and GFP   ⋅   lentivirus expressing Nfyc and GFP   ⋅   lentivirus expressing Taf12 and GFP

0

References: Tong Y, Cancer Cell 2015 May 11;27(5):712-27

CNS - Brain tumor CNS - Brain Plasmid pcDNA3.1 expressing Cre-Recombinase and GFP

observed

References: Tong Y, Cancer Cell 2015 May 11;27(5):712-27