Strain SummaryC57BL/6-Ptentm2Mak Speer6-ps1Tg(Alb-cre)21Mgn/?

Strain Name

C57BL/6-Ptentm2Mak Speer6-ps1Tg(Alb-cre)21Mgn/?

Strain Type(s)

targeted mutation (conditional)  •  transgenic

Strain Synonym(s)

B6-Ptentm2Mak Speer6-ps1Tg(Alb-cre)21Mgn/?  •  B6-Ptentm2Mak Tg(Alb-cre)21Mgn  •  PtenloxP/loxP; Alb-Cre+

Description

Homozygous Ptentm2Mak mice also carrying the Tg(Alb-cre)21Mgn transgene on a C57BL/6 background with possible contribution from 129P2/OlaHsd and/or DBA.

Strain Genetics

Speer6-ps1Tg(Alb-cre)21Mgn / Speer6-ps1?
Speer6-ps1Tg(Alb-cre)21Mgn / Speer6-ps1?
Speer6-ps1Tg(Alb-cre)21Mgn / Speer6-ps1?

Models

14 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Liver - Bile duct cholangiocarcinoma Liver - Bile duct Phosphate Buffered Saline (PBS)

29

References: Zhang J, Cancer Res 2015 May 1;75(9):1859-67

Liver - Bile duct cholangiocarcinoma Liver - Bile duct anti-miR-21

9

References: Zhang J, Cancer Res 2015 May 1;75(9):1859-67

Liver - Bile duct tumor - cholangiolar Liver - Bile duct anti-miR-21

observed

References: Zhang J, Cancer Res 2015 May 1;75(9):1859-67

Liver hepatocellular carcinoma Liver

observed

References: Zhang J, Cancer Res 2015 May 1;75(9):1859-67

Liver hepatocellular carcinoma Liver Phosphate Buffered Saline (PBS)

observed

References: Zhang J, Cancer Res 2015 May 1;75(9):1859-67

Liver hepatocellular carcinoma - heterogeneic Liver Phosphate Buffered Saline (PBS)

observed

References: Zhang J, Cancer Res 2015 May 1;75(9):1859-67

Liver hepatocellular carcinoma - pleomorphic Liver Phosphate Buffered Saline (PBS)

42

References: Zhang J, Cancer Res 2015 May 1;75(9):1859-67

Liver hepatocellular carcinoma - pleomorphic Liver anti-miR-21

27

References: Zhang J, Cancer Res 2015 May 1;75(9):1859-67

Liver hepatocellular carcinoma - well-differentiated Liver anti-miR-21

observed

References: Zhang J, Cancer Res 2015 May 1;75(9):1859-67

Liver hepatocholangiocarcinoma Liver Phosphate Buffered Saline (PBS)

71

References: Zhang J, Cancer Res 2015 May 1;75(9):1859-67

Liver hepatocholangiocarcinoma Liver anti-miR-21

27

References: Zhang J, Cancer Res 2015 May 1;75(9):1859-67

Liver tumor Liver

0 - 100

References: Zhang J, Cancer Res 2015 May 1;75(9):1859-67

Liver tumor Liver anti-miR-21

observed

References: Zhang J, Cancer Res 2015 May 1;75(9):1859-67

Liver tumor Liver Phosphate Buffered Saline (PBS)

observed

References: Zhang J, Cancer Res 2015 May 1;75(9):1859-67