Strain SummaryB6;129S-Atmtm1Bal/+ Atrtm1Bal/+

Strain Name

B6;129S-Atmtm1Bal/+ Atrtm1Bal/+

Strain Type(s)

targeted mutation (knockout)

Strain Synonym(s)

ATR+/-ATM+/-

Description

Double heterozygous mice. The genetic background of these mice was a mixture of C57BL/6 and "129/Sv" (including 129S4/SvJae and possibly some 129S2/SvPas and/or other substrain(s)).

Strain Genetics

Atrtm1Bal / Atr+
Atmtm1Bal / Atm+

Models

6 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Connective tissue - Fibroblast fibroma Ovary

3.3

References: Brown EJ, Genes Dev 2000 Feb 15;14(4):397-402

Leukocyte - Lymphocyte - B-lymphocyte - Follicular center cell lymphoma - mixed Leukocyte - Lymphocyte - B-lymphocyte - Follicular center cell

6.7

References: Brown EJ, Genes Dev 2000 Feb 15;14(4):397-402

Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Leukocyte - Monocyte - Macrophage - Histiocyte

observed

References: Brown EJ, Genes Dev 2000 Feb 15;14(4):397-402

Liver hepatocellular adenoma Liver

3.3

References: Brown EJ, Genes Dev 2000 Feb 15;14(4):397-402

Stomach adenoma Stomach

observed

References: Brown EJ, Genes Dev 2000 Feb 15;14(4):397-402

(Unspecified organ) tumor (Unspecified organ)

13

References: Brown EJ, Genes Dev 2000 Feb 15;14(4):397-402