Mouse Tumor Biology Database (MTB)
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Last Database Update
2020-07-12
MTB 3.0
 
HelpHelp and Documentation Strain Tumor Overview
Collapsed View
 
Strain
C57BL/6J-Trp53tm1Tyj/+ Xpatm1Hvs
Strain Synonyms C57Bl/6J-TgH(XPAIm)55Cmg x C57Bl/6J-TgH(p53Im)Δ26Cmg  •  Xpa-/-/p53+/-  •  XPA/p53
Strain Note: Compound mutant mice. The genetic background of these mice was predominantly C57BL/6J. This cohort was generated by crossing 2 mutant strains each congenic for C57BL/6J.
Strain Tumor Overview Expanded View
Tumors 61 unique tumor types displayed.

A tumor group is a set of tumors that share the same tumor name, organ(s) affected, and treatment type.

Tumor Name Organ(s) Affected Treatment Type Number of
Tumor Group Records
Frequency Range
Adipose tissue lipoma Abdominal cavity None (spontaneous) 2 0 - 0.8
Adipose tissue lipoma CNS - Brain None (spontaneous) 2 0 - 6.7
Adipose tissue lipoma CNS - Brain Hormone 2 0
Adrenal gland - Cortex adenoma Adrenal gland - Cortex None (spontaneous) 2 0 - 2.2
Adrenal gland - Medulla pheochromocytoma Adrenal gland - Medulla None (spontaneous) 4 0
Adrenal gland - Medulla pheochromocytoma Adrenal gland - Medulla Hormone 2 0 - 6.7
Blood vessel hemangiosarcoma Blood vessel None (spontaneous) 2 0 - 1.5
Bone lesion - fibro-osseous Bone None (spontaneous) 2 0 - 6.7
Bone lesion - fibro-osseous Bone Hormone 2 33.3 - 66.7
Bone osteosarcoma Bone None (spontaneous) 6 0 - 0.8
Bone osteosarcoma Bone Hormone 4 0 - 33.3
CNS - Brain glioma CNS - Brain None (spontaneous) 2 0
CNS - Brain glioma CNS - Brain Hormone 2 0 - 6.7
Connective tissue - Fibroblast fibrosarcoma Skin None (spontaneous) 2 0 - 0.8
Connective tissue - Fibroblast fibrosarcoma Uterus - Cervix None (spontaneous) 1 0
Connective tissue - Fibroblast fibrosarcoma Uterus - Cervix Hormone 1 6.7
Gallbladder papilloma Gallbladder Chemical/Drug 2 0 - 13.3
Intestine - Small Intestine tumor Intestine - Small Intestine None (spontaneous) 2 0 - 1.5
Kidney adenoma Kidney Chemical/Drug 1 observed
Kidney hyperplasia Kidney Chemical/Drug 2 observed
Kidney transitional cell carcinoma Kidney Chemical/Drug 3 6.7 - 20
Kidney tumor Kidney Chemical/Drug 2 0 - observed
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Leukocyte - Monocyte - Macrophage - Histiocyte None (spontaneous) 2 0 - 0.8
Leukocyte - Myelocyte (Granulocyte) leukemia - myelocytic Leukocyte - Myelocyte (Granulocyte) None (spontaneous) 2 0
Leukocyte - Myelocyte (Granulocyte) leukemia - myelocytic Leukocyte - Myelocyte (Granulocyte) Hormone 2 0
Leukocyte - Myelocyte (Granulocyte) sarcoma - myeloid Leukocyte - Myelocyte (Granulocyte) None (spontaneous) 2 0
Leukocyte lymphoma Leukocyte None (spontaneous) 8 0 - 13.3
Leukocyte lymphoma Leukocyte Chemical/Drug 4 13.3 - 72.7
Leukocyte lymphoma Leukocyte Hormone 4 0 - 13.3
Liver adenoma Liver None (spontaneous) 2 0
Liver hepatocellular carcinoma Liver None (spontaneous) 2 0
Liver hepatocellular carcinoma Liver Hormone 2 0 - 6.7
Liver tumor Liver Chemical/Drug 5 6.7 - 93.3
Lung adenoma Lung None (spontaneous) 4 0 - 6.7
Lung adenoma Lung Hormone 2 0
Mammary gland adenocarcinoma Mammary gland None (spontaneous) 4 0 - 6.7
Mammary gland adenocarcinoma Mammary gland Hormone 2 0
Mesodermal cell/mesoblast sarcoma CNS - Brain None (spontaneous) 4 0 - 6.7
Mesodermal cell/mesoblast sarcoma Abdominal cavity None (spontaneous) 4 0 - 6.7
Mesodermal cell/mesoblast sarcoma Skin None (spontaneous) 2 40 - 46.7
Mesodermal cell/mesoblast sarcoma Skin Hormone 2 20 - 33.3
Mesodermal cell/mesoblast sarcoma CNS - Brain Hormone 2 0
Mesodermal cell/mesoblast sarcoma Abdominal cavity Hormone 2 0
Muscle - Smooth leiomyosarcoma Muscle - Smooth None (spontaneous) 2 0 - 0.8
Ovary - Germ cell teratoma CNS - Brain None (spontaneous) 1 0
Ovary - Germ cell teratoma CNS - Brain Hormone 1 0
Ovary - Granulosa cell tumor Ovary - Granulosa cell None (spontaneous) 1 0.8
Ovary adenoma - tubulostromal Ovary None (spontaneous) 1 0
Pituitary gland adenoma Pituitary gland None (spontaneous) 2 0
Pituitary gland adenoma Pituitary gland Hormone 2 13.3
Placenta - Decidua deciduoma Placenta - Decidua None (spontaneous) 1 0
Testis - Germ cell teratoma CNS - Brain None (spontaneous) 1 0
Testis - Germ cell teratoma CNS - Brain Hormone 1 6.7
Testis - Leydig cell (Interstitial cell) adenoma Testis - Leydig cell (Interstitial cell) None (spontaneous) 1 0
Testis - Leydig cell (Interstitial cell) adenoma Testis - Leydig cell (Interstitial cell) Hormone 1 33.3
Thymus thymoma Thymus None (spontaneous) 2 0 - 0.8
Thyroid gland - Follicular cell adenoma Thyroid gland - Follicular cell None (spontaneous) 2 0
Urinary bladder tumor Urinary bladder Chemical/Drug 5 13.3 - 60
(Unspecified organ) tumor (Unspecified organ) None (spontaneous) 9 0 - 12.9
(Unspecified organ) tumor (Unspecified organ) Chemical/Drug 5 26.7 - 93.3
(Unspecified organ) tumor (Unspecified organ) Hormone 2 46.7 - 86.7