Strain SummaryC57BL/6J-Ptentm2Mak/+ Tg(KLK3-cre)13Saa

Strain Name

C57BL/6J-Ptentm2Mak/+ Tg(KLK3-cre)13Saa

Strain Type(s)

targeted mutation (conditional)  •  transgenic

Strain Synonym(s)

PSACre;PTENloxP/+

Description

Heterozygous Ptentm2Mak mice on a "pure C57BL/6J background strain" carrying the Tg(KLK3-cre)13Saa transgene. The Ptentm2Mak allele was originally generated on a 129P2/OlaHsd background.

Strain Genetics

Tg(KLK3-cre)13Saa
Ptentm2Mak / Pten+

Models

3 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Prostate gland lesion Prostate gland

0 - 92.31

References: De Velasco MA, Carcinogenesis 2014 Sep;35(9):2142-53

Prostate gland prostatic intraepithelial neoplasia (PIN) Prostate gland

0 - 38.46

References: De Velasco MA, Carcinogenesis 2014 Sep;35(9):2142-53

Prostate gland tumor Prostate gland

0 - 53.85

References: De Velasco MA, Carcinogenesis 2014 Sep;35(9):2142-53

Sites of Metastasis: not (Unspecified organ)