Strain SummaryC57BL/6J-Ptentm2Mak Tg(KLK3-cre)13Saa

Strain Name

C57BL/6J-Ptentm2Mak Tg(KLK3-cre)13Saa

Strain Type(s)

targeted mutation (conditional)  •  transgenic

Strain Synonym(s)

PSACre;PTENloxP/loxP

Description

Homozygous Ptentm2Mak mice on a "pure C57BL/6J background strain" carrying the Tg(KLK3-cre)13Saa transgene. The Ptentm2Mak allele was originally generated on a 129P2/OlaHsd background.

Strain Genetics

Tg(KLK3-cre)13Saa

Models

15 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Prostate gland - Anterior lobe adenocarcinoma Prostate gland - Anterior lobe

low

References: De Velasco MA, Carcinogenesis 2014 Sep;35(9):2142-53

Prostate gland - Dorsal lobe adenocarcinoma Prostate gland - Dorsal lobe

100

References: De Velasco MA, Carcinogenesis 2014 Sep;35(9):2142-53

Prostate gland - Dorsal lobe tumor - well-differentiated Prostate gland - Dorsal lobe

very high

References: De Velasco MA, Carcinogenesis 2014 Sep;35(9):2142-53

Prostate gland - Lateral lobe adenocarcinoma Prostate gland - Lateral lobe

100

References: De Velasco MA, Carcinogenesis 2014 Sep;35(9):2142-53

Prostate gland - Lateral lobe tumor - well-differentiated Prostate gland - Lateral lobe

very high

References: De Velasco MA, Carcinogenesis 2014 Sep;35(9):2142-53

Prostate gland - Ventral lobe adenocarcinoma Prostate gland - Ventral lobe

100

References: De Velasco MA, Carcinogenesis 2014 Sep;35(9):2142-53

Prostate gland adenocarcinoma Prostate gland

100

References: De Velasco MA, Carcinogenesis 2014 Sep;35(9):2142-53

Prostate gland lesion Prostate gland

0 - 100

References: De Velasco MA, Carcinogenesis 2014 Sep;35(9):2142-53

Prostate gland prostatic intraepithelial neoplasia (PIN) Prostate gland

0 - 46.15

References: De Velasco MA, Carcinogenesis 2014 Sep;35(9):2142-53

Prostate gland prostatic intraepithelial neoplasia - grade 1 (PIN I) Prostate gland

0

References: De Velasco MA, Carcinogenesis 2014 Sep;35(9):2142-53

Prostate gland tumor Prostate gland

0 - 100

References: De Velasco MA, Carcinogenesis 2014 Sep;35(9):2142-53

Sites of Metastasis: (Unspecified organ) , not (Unspecified organ) , Liver , Lung , Lymph node

Prostate gland tumor Prostate gland Everolimus

observed

References: De Velasco MA, Carcinogenesis 2014 Sep;35(9):2142-53

Prostate gland tumor Prostate gland U0126

observed

References: De Velasco MA, Carcinogenesis 2014 Sep;35(9):2142-53

Prostate gland tumor Prostate gland Everolimus   ⋅   U0126

observed

References: De Velasco MA, Carcinogenesis 2014 Sep;35(9):2142-53

Prostate gland tumor - well-differentiated Prostate gland

very high

References: De Velasco MA, Carcinogenesis 2014 Sep;35(9):2142-53