Strain Summary[not specified]-Gt(ROSA)26Sortm1Sor Ptentm2Mak Tg(Cyp1a1-cre)1Dwi

Strain Name

[not specified]-Gt(ROSA)26Sortm1Sor Ptentm2Mak Tg(Cyp1a1-cre)1Dwi

Strain Type(s)

targeted mutation (conditional)  •  targeted mutation (knock-in)  •  transgenic

Strain Synonym(s)

cre+;Ptenf/f

Description

Homozygous Pten mice also carrying Tg(Cyp1a1-cre/ERT)1Dwi and Gt(ROSA)26Sortm1Sor on an unspecified background with possible contribution from 129S4/SvJaeSor, CBA, 129P2/OlaHsd, and/or C57BL/6.

Strain Genetics

Gt(ROSA)26Sortm1Sor
Tg(Cyp1a1-cre)1Dwi

Models

4 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Intestine lesion - hamartomatous Intestine beta-naphthoflavone (betaNF)

0

References: Marsh V, Nat Genet 2008 Dec;40(12):1436-44

Leukocyte lymphoma Leukocyte beta-naphthoflavone (betaNF)

observed

References: Marsh V, Nat Genet 2008 Dec;40(12):1436-44

Liver hepatocellular adenoma Liver beta-naphthoflavone (betaNF)

observed

References: Marsh V, Nat Genet 2008 Dec;40(12):1436-44

Uterus - Endometrium hyperplasia - atypical - complex Uterus - Endometrium beta-naphthoflavone (betaNF)

observed

References: Marsh V, Nat Genet 2008 Dec;40(12):1436-44