Strain Summary[not specified]-Ptentm2Mak Tg(Cyp1a1-cre/ERT)1Dwi

Strain Name

[not specified]-Ptentm2Mak Tg(Cyp1a1-cre/ERT)1Dwi

Strain Type(s)

targeted mutation (conditional)  •  transgenic

Strain Synonym(s)

Ah::CreERT/0;PtenF/F  •  AhCreERT+; Ptenf/f; Apc+/+  •  PtenF/F

Description

Homozygous Pten mutant mice carrying the Tg(Cyp1a1-cre/ERT)1Dwi transgene on an unspecified background with possible contribution from 129P2/OlaHsd, CBA, 129S4/SvJae, and/or C57BL/6.

Strain Genetics

Tg(Cyp1a1-cre/ERT)1Dwi
Tg(Cyp1a1-cre/ERT)1Dwi

Models

28 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Intestine - Large Intestine - Colon adenocarcinoma Intestine - Large Intestine - Colon tamoxifen (For inducing expression from mutant alleles)   ⋅   beta-naphthoflavone (betaNF)

observed

References: Marsh Durban V, Am J Pathol 2014 Jan;184(1):86-91

Intestine - Large Intestine - Colon dysplasia Intestine - Large Intestine - Colon tamoxifen (For inducing expression from mutant alleles)   ⋅   beta-naphthoflavone (betaNF)

observed

References: Marsh Durban V, Am J Pathol 2014 Jan;184(1):86-91

Intestine - Large Intestine - Colon lesion Intestine - Large Intestine - Colon tamoxifen (For inducing expression from mutant alleles)   ⋅   beta-naphthoflavone (betaNF)

observed

References: Marsh Durban V, Am J Pathol 2014 Jan;184(1):86-91

Intestine - Large Intestine - Colon lesion - epithelial Intestine - Large Intestine - Colon tamoxifen (For inducing expression from mutant alleles)   ⋅   beta-naphthoflavone (betaNF)

observed

References: Marsh Durban V, Am J Pathol 2014 Jan;184(1):86-91

Intestine - Large Intestine - Colon polyp Intestine - Large Intestine - Colon tamoxifen (For inducing expression from mutant alleles)   ⋅   beta-naphthoflavone (betaNF)

observed

References: Marsh Durban V, Am J Pathol 2014 Jan;184(1):86-91

Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon tamoxifen (For inducing expression from mutant alleles)   ⋅   beta-naphthoflavone (betaNF)

observed

References: Marsh Durban V, Am J Pathol 2014 Jan;184(1):86-91

Intestine - Large Intestine adenocarcinoma Intestine - Large Intestine tamoxifen (For inducing expression from mutant alleles)   ⋅   beta-naphthoflavone (betaNF)

4.35

References: Marsh Durban V, Am J Pathol 2014 Jan;184(1):86-91

Intestine - Large Intestine adenoma - tubular Intestine - Large Intestine tamoxifen (For inducing expression from mutant alleles)   ⋅   beta-naphthoflavone (betaNF)

0

References: Marsh Durban V, Am J Pathol 2014 Jan;184(1):86-91

Intestine - Large Intestine carcinoma - invasive Intestine - Large Intestine tamoxifen (For inducing expression from mutant alleles)   ⋅   beta-naphthoflavone (betaNF)

observed

References: Marsh Durban V, Am J Pathol 2014 Jan;184(1):86-91

Intestine - Large Intestine dysplasia Intestine - Large Intestine tamoxifen (For inducing expression from mutant alleles)   ⋅   beta-naphthoflavone (betaNF)

observed

References: Marsh Durban V, Am J Pathol 2014 Jan;184(1):86-91

Intestine - Large Intestine dysplasia - focal Intestine - Large Intestine tamoxifen (For inducing expression from mutant alleles)   ⋅   beta-naphthoflavone (betaNF)

observed

References: Marsh Durban V, Am J Pathol 2014 Jan;184(1):86-91

Intestine - Large Intestine lesion Intestine - Large Intestine tamoxifen (For inducing expression from mutant alleles)   ⋅   beta-naphthoflavone (betaNF)

observed

References: Marsh Durban V, Am J Pathol 2014 Jan;184(1):86-91

Intestine - Large Intestine lesion - polypoid Intestine - Large Intestine tamoxifen (For inducing expression from mutant alleles)   ⋅   beta-naphthoflavone (betaNF)

100

References: Marsh Durban V, Am J Pathol 2014 Jan;184(1):86-91

Intestine - Large Intestine neoplasia - intraepithelial Intestine - Large Intestine tamoxifen (For inducing expression from mutant alleles)   ⋅   beta-naphthoflavone (betaNF)

observed

References: Marsh Durban V, Am J Pathol 2014 Jan;184(1):86-91

Intestine - Large Intestine polyp Intestine - Large Intestine tamoxifen (For inducing expression from mutant alleles)   ⋅   beta-naphthoflavone (betaNF)

observed

References: Marsh Durban V, Am J Pathol 2014 Jan;184(1):86-91

Intestine - Large Intestine polyp - adenomatous Intestine - Large Intestine tamoxifen (For inducing expression from mutant alleles)   ⋅   beta-naphthoflavone (betaNF)

0

References: Marsh Durban V, Am J Pathol 2014 Jan;184(1):86-91

Intestine - Large Intestine polyp - hyperplastic Intestine - Large Intestine tamoxifen (For inducing expression from mutant alleles)   ⋅   beta-naphthoflavone (betaNF)

0

References: Marsh Durban V, Am J Pathol 2014 Jan;184(1):86-91

Intestine - Large Intestine tumor Intestine - Large Intestine tamoxifen (For inducing expression from mutant alleles)   ⋅   beta-naphthoflavone (betaNF)

observed

References: Marsh Durban V, Am J Pathol 2014 Jan;184(1):86-91

Intestine - Small Intestine adenocarcinoma Intestine - Small Intestine tamoxifen (For inducing expression from mutant alleles)   ⋅   beta-naphthoflavone (betaNF)

observed

References: Marsh Durban V, Am J Pathol 2014 Jan;184(1):86-91

Intestine - Small Intestine adenoma - tubular Intestine - Small Intestine tamoxifen (For inducing expression from mutant alleles)   ⋅   beta-naphthoflavone (betaNF)

observed - 4.35

References: Marsh Durban V, Am J Pathol 2014 Jan;184(1):86-91

Intestine - Small Intestine dysplasia - low grade Intestine - Small Intestine tamoxifen (For inducing expression from mutant alleles)   ⋅   beta-naphthoflavone (betaNF)

4.35

References: Marsh Durban V, Am J Pathol 2014 Jan;184(1):86-91

Intestine - Small Intestine lesion Intestine - Small Intestine tamoxifen (For inducing expression from mutant alleles)   ⋅   beta-naphthoflavone (betaNF)

observed

References: Marsh Durban V, Am J Pathol 2014 Jan;184(1):86-91

Intestine - Small Intestine tumor Intestine - Small Intestine tamoxifen (For inducing expression from mutant alleles)   ⋅   beta-naphthoflavone (betaNF)

observed

References: Marsh Durban V, Am J Pathol 2014 Jan;184(1):86-91

Intestine dysplasia - low grade Intestine tamoxifen (For inducing expression from mutant alleles)   ⋅   beta-naphthoflavone (betaNF)

observed

References: Marsh Durban V, Am J Pathol 2014 Jan;184(1):86-91

Intestine hamartoma Intestine tamoxifen (For inducing expression from mutant alleles)   ⋅   beta-naphthoflavone (betaNF)

0

References: Marsh V, Nat Genet 2008 Dec;40(12):1436-44

Intestine lesion Intestine tamoxifen (For inducing expression from mutant alleles)   ⋅   beta-naphthoflavone (betaNF)

56.52

References: Marsh Durban V, Am J Pathol 2014 Jan;184(1):86-91

Intestine polyp Intestine tamoxifen (For inducing expression from mutant alleles)   ⋅   beta-naphthoflavone (betaNF)

56.52

References: Marsh Durban V, Am J Pathol 2014 Jan;184(1):86-91

Prostate gland neoplasia Prostate gland tamoxifen (For inducing expression from mutant alleles)   ⋅   beta-naphthoflavone (betaNF)

observed

References: Marsh Durban V, Am J Pathol 2014 Jan;184(1):86-91