Strain SummaryB6;FVB-Gt(ROSA)26Sortm1Sor Ptentm1Mro Trp53tm1Brn

Strain Name

B6;FVB-Gt(ROSA)26Sortm1Sor Ptentm1Mro Trp53tm1Brn

Strain Type(s)

targeted mutation (conditional)  •  targeted mutation (knock-in)

Strain Synonym(s)

p53/Pten

Description

Homozygous mice on a mixed C57BL/6, FVB background with possible contributions from 129S4/SvJae and 129P2/OlaHsd.

Models

7 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
CNS - Brain - Astrocyte astrocytoma - anaplastic CNS - Brain - Astrocyte Adenovirus carrying cre recombinase

observed

References: Henriquez NV, Cancer Res 2013 Sep 15;73(18):5834-44

CNS - Brain - Oligodendroglial cell oligodendroglioma CNS - Brain - Oligodendroglial cell Adenovirus carrying cre recombinase

observed

References: Henriquez NV, Cancer Res 2013 Sep 15;73(18):5834-44

CNS - Brain - Undifferentiated cell primitive neuroectodermal tumor (PNET) CNS - Brain - Cerebrum Adenovirus carrying cre recombinase

0

References: Henriquez NV, Cancer Res 2013 Sep 15;73(18):5834-44

CNS - Brain glioblastoma CNS - Brain Adenovirus carrying cre recombinase

0

References: Henriquez NV, Cancer Res 2013 Sep 15;73(18):5834-44

CNS - Brain glioma CNS - Brain Adenovirus carrying cre recombinase

observed - 24.14

References: Henriquez NV, Cancer Res 2013 Sep 15;73(18):5834-44

CNS - Brain oligoastrocytoma - anaplastic CNS - Brain Adenovirus carrying cre recombinase

observed

References: Henriquez NV, Cancer Res 2013 Sep 15;73(18):5834-44

CNS - Brain tumor CNS - Brain Adenovirus carrying cre recombinase

observed - 24.14

References: Henriquez NV, Cancer Res 2013 Sep 15;73(18):5834-44