Strain SummaryB6;129S5-Gt(ROSA)26Sortm1(sb11)Njen Hprttm1(sb-Onco-Array)Peli/+

Strain Name

B6;129S5-Gt(ROSA)26Sortm1(sb11)Njen Hprttm1(sb-Onco-Array)Peli/+

Strain Type(s)

targeted mutation (knock-in)  •  targeted mutation (other)

Strain Synonym(s)

Onc/+; SB/+

Description

Compound mutant mice. The genetic background of these mice was reported to be C57BL/6 and 129S5. It also included at least some 129S7/SvEvBrd-Hprt+ and possibly some other strain(s).

Strain Genetics

Hprttm1(sb-Onco-Array)Peli / Hprt+
Hprttm1(sb-Onco-Array)Peli
Hprttm1(sb-Onco-Array)Peli
Hprttm1(sb-Onco-Array)Peli / Hprt+
Hprttm1(sb-Onco-Array)Peli
Hprttm1(sb-Onco-Array)Peli / Hprt+
Hprttm1(sb-Onco-Array)Peli / Hprt+
Gt(ROSA)26Sortm1(sb11)Njen
Hprttm1(sb-Onco-Array)Peli
Hprttm1(sb-Onco-Array)Peli / Hprt+
Hprttm1(sb-Onco-Array)Peli / Hprt+
Hprttm1(sb-Onco-Array)Peli
Hprttm1(sb-Onco-Array)Peli
Gt(ROSA)26Sortm1(sb11)Njen

Models

28 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Blood vessel hemangioblastoma - capillary CNS - Brain

observed

References: Su Q, Proc Natl Acad Sci U S A 2008 Dec 16;105(50):19904-9

Blood vessel hemangioma Skin

observed

References: Su Q, Proc Natl Acad Sci U S A 2008 Dec 16;105(50):19904-9

Blood vessel hemangioma - capillary CNS - Brain

observed

References: Su Q, Proc Natl Acad Sci U S A 2008 Dec 16;105(50):19904-9

CNS - Brain - Cerebrum - Cortex - Cortical layer II hyperplasia CNS - Brain - Cerebrum - Cortex - Cortical layer II

observed

References: Su Q, Proc Natl Acad Sci U S A 2008 Dec 16;105(50):19904-9

CNS - Brain - Oligodendroglial cell oligodendroglioma CNS - Brain - Oligodendroglial cell

observed

References: Su Q, Proc Natl Acad Sci U S A 2008 Dec 16;105(50):19904-9

CNS - Brain glioma CNS - Brain

observed

References: Su Q, Proc Natl Acad Sci U S A 2008 Dec 16;105(50):19904-9

CNS - Brain medulloblastoma CNS - Brain

observed

References: Su Q, Proc Natl Acad Sci U S A 2008 Dec 16;105(50):19904-9

3 pathology image(s)

Connective tissue - Fibroblast fibrosarcoma Connective tissue - Fibroblast

observed

References: Su Q, Proc Natl Acad Sci U S A 2008 Dec 16;105(50):19904-9

Germ cell (sex not specified) teratoma Thymus

observed

References: Su Q, Proc Natl Acad Sci U S A 2008 Dec 16;105(50):19904-9

Intestine tumor Intestine

observed

References: Su Q, Proc Natl Acad Sci U S A 2008 Dec 16;105(50):19904-9

Leg tumor Leg

observed

References: Su Q, Proc Natl Acad Sci U S A 2008 Dec 16;105(50):19904-9

Leukocyte - Myelocyte (Granulocyte) hyperplasia Liver

observed

References: Su Q, Proc Natl Acad Sci U S A 2008 Dec 16;105(50):19904-9

Leukocyte - Myelocyte (Granulocyte) hyperplasia Spleen

observed

References: Su Q, Proc Natl Acad Sci U S A 2008 Dec 16;105(50):19904-9

Leukocyte hyperplasia Spleen

observed

References: Su Q, Proc Natl Acad Sci U S A 2008 Dec 16;105(50):19904-9

Leukocyte lymphoma Spleen

observed

References: Su Q, Proc Natl Acad Sci U S A 2008 Dec 16;105(50):19904-9

Lung adenocarcinoma Lung

observed

References: Su Q, Proc Natl Acad Sci U S A 2008 Dec 16;105(50):19904-9

Lung adenoma Lung

observed

References: Su Q, Proc Natl Acad Sci U S A 2008 Dec 16;105(50):19904-9

Lung carcinoma Lung

observed

References: Su Q, Proc Natl Acad Sci U S A 2008 Dec 16;105(50):19904-9

1 pathology image(s)

Lung squamous cell carcinoma - poorly differentiated Lung

observed

References: Su Q, Proc Natl Acad Sci U S A 2008 Dec 16;105(50):19904-9

Mesothelium mesothelioma Mesothelium

observed

References: Su Q, Proc Natl Acad Sci U S A 2008 Dec 16;105(50):19904-9

Muscle - Striated - Cardiac rhabdomyosarcoma Muscle - Striated - Cardiac

observed

References: Su Q, Proc Natl Acad Sci U S A 2008 Dec 16;105(50):19904-9

3 pathology image(s)

Skin - Dermis lesion Skin - Dermis

observed

References: Su Q, Proc Natl Acad Sci U S A 2008 Dec 16;105(50):19904-9

Skin - Dermis tumor - spindle cell Skin - Dermis

observed

References: Su Q, Proc Natl Acad Sci U S A 2008 Dec 16;105(50):19904-9

Skin squamous cell carcinoma - well differentiated Skin

observed

References: Su Q, Proc Natl Acad Sci U S A 2008 Dec 16;105(50):19904-9

1 pathology image(s)

Spleen lesion Spleen

observed

References: Su Q, Proc Natl Acad Sci U S A 2008 Dec 16;105(50):19904-9

1 pathology image(s)

(Unspecified organ) angiosarcoma CNS - Brain

observed

References: Su Q, Proc Natl Acad Sci U S A 2008 Dec 16;105(50):19904-9

3 pathology image(s)

(Unspecified organ) angiosarcoma Skin

observed

References: Su Q, Proc Natl Acad Sci U S A 2008 Dec 16;105(50):19904-9

(Unspecified organ) tumor (Unspecified organ)

100

References: Su Q, Proc Natl Acad Sci U S A 2008 Dec 16;105(50):19904-9