Strain Summary[not specified]-Ptentm2Mak Tg(Cyp1a1-cre/ERT)1Dwi

Strain Name

[not specified]-Ptentm2Mak Tg(Cyp1a1-cre/ERT)1Dwi

Strain Type(s)

targeted mutation (conditional)  •  transgenic

Strain Synonym(s)

AhCreERT+;Ptenf/f  •  Ptenf/f

Description

Homozygous Pten mice on an unspecified background and carrying the Tg(Cyp1a1-cre/ERT)1Dwi transgene. Mice may have had contributions from 129P2/OlaHsd, CBA, and/or C57BL/6.

Strain Genetics

Tg(Cyp1a1-cre/ERT)1Dwi
Tg(Cyp1a1-cre/ERT)1Dwi

Models

16 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Gallbladder hyperplasia Gallbladder tamoxifen (For inducing expression from mutant alleles)   ⋅   beta-naphthoflavone (betaNF)

observed

References: Marsh V, J Pathol 2013 Jun;230(2):165-73

Liver - Bile duct adenoma Liver - Bile duct tamoxifen (For inducing expression from mutant alleles)   ⋅   beta-naphthoflavone (betaNF)

observed - 45.83

References: Marsh V, J Pathol 2013 Jun;230(2):165-73

Liver - Bile duct cholangiocarcinoma Liver - Bile duct tamoxifen (For inducing expression from mutant alleles)   ⋅   beta-naphthoflavone (betaNF)

observed

References: Marsh V, J Pathol 2013 Jun;230(2):165-73

Liver - Bile duct hamartoma Liver - Bile duct tamoxifen (For inducing expression from mutant alleles)   ⋅   beta-naphthoflavone (betaNF)

observed

References: Marsh V, J Pathol 2013 Jun;230(2):165-73

Liver - Bile duct hyperplasia Liver - Bile duct tamoxifen (For inducing expression from mutant alleles)   ⋅   beta-naphthoflavone (betaNF)

observed

References: Marsh V, J Pathol 2013 Jun;230(2):165-73

Liver - Bile duct hyperplasia - epithelial Liver - Bile duct tamoxifen (For inducing expression from mutant alleles)   ⋅   beta-naphthoflavone (betaNF)

16.67

References: Marsh V, J Pathol 2013 Jun;230(2):165-73

Liver - Bile duct hyperplasia - lobular Liver - Bile duct tamoxifen (For inducing expression from mutant alleles)   ⋅   beta-naphthoflavone (betaNF)

observed

References: Marsh V, J Pathol 2013 Jun;230(2):165-73

Liver - Bile duct lesion Liver - Bile duct tamoxifen (For inducing expression from mutant alleles)   ⋅   beta-naphthoflavone (betaNF)

observed - 58.33

References: Marsh V, J Pathol 2013 Jun;230(2):165-73

Liver - Bile duct neoplasm - mixed Liver - Bile duct tamoxifen (For inducing expression from mutant alleles)   ⋅   beta-naphthoflavone (betaNF)

29.17

References: Marsh V, J Pathol 2013 Jun;230(2):165-73

Liver - Hepatocyte lesion Liver - Hepatocyte tamoxifen (For inducing expression from mutant alleles)   ⋅   beta-naphthoflavone (betaNF)

observed

References: Marsh V, J Pathol 2013 Jun;230(2):165-73

Liver adenoma Liver tamoxifen (For inducing expression from mutant alleles)   ⋅   beta-naphthoflavone (betaNF)

observed

References: Marsh V, J Pathol 2013 Jun;230(2):165-73

Liver hepatocellular carcinoma Liver tamoxifen (For inducing expression from mutant alleles)   ⋅   beta-naphthoflavone (betaNF)

observed

References: Marsh V, J Pathol 2013 Jun;230(2):165-73

Liver lesion Liver tamoxifen (For inducing expression from mutant alleles)   ⋅   beta-naphthoflavone (betaNF)

observed

References: Marsh V, J Pathol 2013 Jun;230(2):165-73

Liver neoplasm Liver tamoxifen (For inducing expression from mutant alleles)   ⋅   beta-naphthoflavone (betaNF)

observed

References: Marsh V, J Pathol 2013 Jun;230(2):165-73

Liver neoplasm - mixed Liver tamoxifen (For inducing expression from mutant alleles)   ⋅   beta-naphthoflavone (betaNF)

observed

References: Marsh V, J Pathol 2013 Jun;230(2):165-73

Prostate gland neoplasia Prostate gland tamoxifen (For inducing expression from mutant alleles)   ⋅   beta-naphthoflavone (betaNF)

high

References: Marsh V, J Pathol 2013 Jun;230(2):165-73