Strain SummarySTOCK Ptentm1Hwu/+ Tg(KRT14-cre/ERT)20Efu Tgfbr1tm1.1Karl/+

Strain Name

STOCK Ptentm1Hwu/+ Tg(KRT14-cre/ERT)20Efu Tgfbr1tm1.1Karl/+

Strain Type(s)

targeted mutation (conditional)  •  transgenic

Strain Synonym(s)

K14-CreERtam; Tgfbr1f/+;Ptenf/+

Description

Heterozygous Pten, Tgfbr1, and transgenic mice on a mixed background. Mice had contributions from FVB/N, C57BL/6, 129/SvJ, CD-1, 129, and 129S4/SvJae.

Strain Genetics

Tg(KRT14-cre/ERT)20Efu
Ptentm1Hwu / Pten+
Tgfbr1tm1.1Karl / Tgfbr1+

Models

1 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Skin tumor Skin tamoxifen (For inducing expression from mutant alleles)

0

References: Bian Y, Oncogene 2012 Jul 12;31(28):3322-32