Mouse Tumor Biology Database (MTB)
MTB Home   Help
Search for Help
in these sections
Search Forms
Pathology Images
Search MTB Using Human Genes
Gene Expression Data Sets

Additional Resources
new PDX Like Me
PDX Finder
PDX Model Search
Faceted Tumor Search
Dynamic Tumor Frequency Grid
Other Cancer Websites
Lymphoma Pathology

Mouse Genome Informatics
The Jackson Laboratory
Citing These Resources
Warranty Disclaimer
& Copyright Notice

Send Questions and
Comments to User Support.

Last Database Update
MTB 3.0
HelpHelp and Documentation Strain Tumor Overview
Collapsed View
B6;129-Cdkn2atm1Cjs/+ Trp53tm1Tyj
Strain Synonyms a+/-p-/-m+/+  •  Mdm2+/+Arf+/-p53-/-  •  m+/+a+/-p-/-
Strain Note: Compound mutant mice. The genetic background of these mice was a mixture of C57BL/6 (64%) and 129/Sv (36%). The "129/Sv" was a combination of at least 129S2/SvPas, 129S7/SvEvBrd-Hprt+, and 129X1/SvJ.
Strain Tumor Overview Expanded View
Tumors 12 unique tumor types displayed.

A tumor group is a set of tumors that share the same tumor name, organ(s) affected, and treatment type.

Tumor Name Organ(s) Affected Treatment Type Number of
Tumor Group Records
Frequency Range
Blood vessel hemangioma Blood vessel None (spontaneous) 1 0
Blood vessel hemangiosarcoma Blood vessel None (spontaneous) 1 29
Bone osteosarcoma Bone None (spontaneous) 1 0
CNS tumor CNS None (spontaneous) 1 0
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Leukocyte - Monocyte - Macrophage - Histiocyte None (spontaneous) 1 5.9
Leukocyte lymphoma Leukocyte None (spontaneous) 1 59
Mesodermal cell/mesoblast sarcoma Mesodermal cell/mesoblast None (spontaneous) 2 24 - 59
Muscle - Smooth leiomyoma Muscle - Smooth None (spontaneous) 1 0
(Unspecified organ) adenoma (Unspecified organ) None (spontaneous) 1 0
(Unspecified organ) carcinoma (Unspecified organ) None (spontaneous) 1 12
(Unspecified organ) carcinosarcoma (Unspecified organ) None (spontaneous) 1 0
(Unspecified organ) tumor (Unspecified organ) None (spontaneous) 1 100