Strain Summary[not specified]-Apctm1Rak/+ Gt(ROSA)26Sortm4(Ikbkb)Rsky/Gt(ROSA)26Sor Tg(Vil1-cre)997Gum

Strain Name

[not specified]-Apctm1Rak/+ Gt(ROSA)26Sortm4(Ikbkb)Rsky/Gt(ROSA)26Sor Tg(Vil1-cre)997Gum

Strain Type(s)

targeted mutation (conditional)  •  targeted mutation (knockout)  •  transgenic

Strain Synonym(s)

APC1638N/IKK2caIEChet  •  [not specified]-Apctm1Rak/+ Gt(ROSA)26Sortm4(Ikbkb)Rsky/Gt(ROSA)26Sor Tg(Vil-cre)997Gum

Description

Heterozygous mice containing one copy of the Gt(ROSA)26Sortm4(Ikbkb)Rsky conditional allele and the Tg(Vil1-cre)997Gum transgene on an unspecified background with possible contributions from C57BL/6, 129P2/OlaHsd, and SJL.

Strain Genetics

Apctm1Rak / Apc+
Tg(Vil1-cre)997Gum
Gt(ROSA)26Sortm4(Ikbkb)Rsky / Gt(ROSA)26Sor
Gt(ROSA)26Sortm4(Ikbkb)Rsky / Gt(ROSA)26Sor
Gt(ROSA)26Sortm4(Ikbkb)Rsky / Gt(ROSA)26Sor

Models

9 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Intestine - Large Intestine - Colon adenoma Intestine - Large Intestine - Colon

observed

References: Vlantis K, J Clin Invest 2011 Jul 1;121(7):2781-93

Intestine - Large Intestine - Colon dysplasia Intestine - Large Intestine - Colon

observed

References: Vlantis K, J Clin Invest 2011 Jul 1;121(7):2781-93

Intestine - Large Intestine - Colon polyp Intestine - Large Intestine - Colon

observed - 100

References: Vlantis K, J Clin Invest 2011 Jul 1;121(7):2781-93

Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon

100

References: Vlantis K, J Clin Invest 2011 Jul 1;121(7):2781-93

Intestine - Small Intestine - Proximal polyp Intestine - Small Intestine - Proximal

observed

References: Vlantis K, J Clin Invest 2011 Jul 1;121(7):2781-93

Intestine - Small Intestine - Proximal tumor Intestine - Small Intestine - Proximal

100

References: Vlantis K, J Clin Invest 2011 Jul 1;121(7):2781-93

Intestine - Small Intestine dysplasia Intestine - Small Intestine

observed

References: Vlantis K, J Clin Invest 2011 Jul 1;121(7):2781-93

Intestine - Small Intestine polyp Intestine - Small Intestine

100

References: Vlantis K, J Clin Invest 2011 Jul 1;121(7):2781-93

Intestine - Small Intestine polyp - adenomatous Intestine - Small Intestine

observed

References: Vlantis K, J Clin Invest 2011 Jul 1;121(7):2781-93