Strain SummaryB6.129-Apctm1.1Alew/+

Strain Name

B6.129-Apctm1.1Alew/+

Strain Type(s)

congenic  •  targeted mutation (knockout)

Strain Synonym(s)

1322T  •  C57BL/6J-Apctm1.1Alew/+

Description

Heterozygous mice on a C57BL/6J background. Mice were bred to wild-type C57BL/6J for at least 6 generations but may have contained contributions from 129.

Strain Genetics

Apctm1.1Alew / Apc+

Models

5 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Gastrointestinal tract adenoma Gastrointestinal tract

100

References: Pollard P, Gastroenterology 2009 Jun;136(7):2204-2213.e1-13

Gastrointestinal tract foci - aberrant crypt (ACF) Gastrointestinal tract

0

References: Pollard P, Gastroenterology 2009 Jun;136(7):2204-2213.e1-13

Intestine - Large Intestine - Colon polyp Intestine - Large Intestine - Colon

observed

References: Pollard P, Gastroenterology 2009 Jun;136(7):2204-2213.e1-13

Intestine - Small Intestine adenoma Intestine - Small Intestine

observed

References: Pollard P, Gastroenterology 2009 Jun;136(7):2204-2213.e1-13

Intestine - Small Intestine dysplasia Intestine - Small Intestine

observed

References: Pollard P, Gastroenterology 2009 Jun;136(7):2204-2213.e1-13