Strain Summary[not specified]-Cdkn2atm4Rdp Krastm3Tyj/+ Tg(Pdx1-cre/Esr1*)#Dam

Strain Name

[not specified]-Cdkn2atm4Rdp Krastm3Tyj/+ Tg(Pdx1-cre/Esr1*)#Dam

Strain Type(s)

targeted mutation (conditional)  •  targeted mutation (knock-in)  •  transgenic

Strain Synonym(s)

Pdx1-Cre;KrasLSL-G12D;Ink4a/ArfF/F

Description

Heterozygous Kras, homozygous Cdkn2a, transgenic mice on an unspecified genetic background with contributions from at least 129S2/SvPas, C57BL/6, and CBA.

Strain Genetics

Krastm3Tyj / Kras+
Tg(Pdx1-cre/Esr1*)#Dam
Tg(Pdx1-cre/Esr1*)#Dam

Models

3 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Pancreas - Duct cyst Pancreas - Duct

100

References: Ling J, Cancer Cell 2012 Jan 17;21(1):105-20

Pancreas adenocarcinoma - ductal Pancreas

100

References: Ling J, Cancer Cell 2012 Jan 17;21(1):105-20

Pancreas pancreatic intraepithelial neoplasia (PanIN) Pancreas

100

References: Ling J, Cancer Cell 2012 Jan 17;21(1):105-20