Strain SummaryB6;129-Rb1tm3Tyj Rbl2tm2Tyj Smotm2Amc Trp53tm1Brn

Strain Name

B6;129-Rb1tm3Tyj Rbl2tm2Tyj Smotm2Amc Trp53tm1Brn

Strain Type(s)

targeted mutation (conditional)

Strain Synonym(s)

Rb1lox/lox; Trp53lox/lox; Rbl2lox/lox; Smolox/lox

Description

Homozygous Rb1, Rbl2, Trp53, Smo mutant mice on a mixed C57BL/6, 129 background. 129 contributions were from at least 129X1/SvJ, 129S4/SvJae, 129P2/OlaHsd, 129/SvJ, and 129/Ola.

Models

1 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Lung carcinoma - small cell lung (SCLC) Lung Adenovirus - recombinant, expressing Cre recombinase

observed

References: Park KS, Nat Med 2011;17(11):1504-8