Strain SummaryB6;129-Trp53tm1Glo/+

Strain Name

B6;129-Trp53tm1Glo/+

Strain Type(s)

targeted mutation (knock-in)

Strain Synonym(s)

Csn6+/+p53+/-  •  p53+/-

Description

Heterozygous mice. The genetic background of these mice was a mixture of C57BL/6J and 129 (129S7/SvEvBrd-Hprt+ and likely some 129P2/OlaHsd).

Strain Genetics

Trp53tm1Glo / Trp53+

Models

12 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Blood vessel tumor - benign Blood vessel gamma-radiation

0

References: Zhao R, J Clin Invest 2011 Mar 1;121(3):851-65

Intestine - Small Intestine adenoma Intestine - Small Intestine gamma-radiation

0

References: Zhao R, J Clin Invest 2011 Mar 1;121(3):851-65

Leukocyte lymphoma - high-grade Leukocyte gamma-radiation

70.6

References: Zhao R, J Clin Invest 2011 Mar 1;121(3):851-65

Leukocyte lymphoma - low-grade Leukocyte gamma-radiation

0

References: Zhao R, J Clin Invest 2011 Mar 1;121(3):851-65

Lung carcinoma - neuroendocrine Lung gamma-radiation

0

References: Zhao R, J Clin Invest 2011 Mar 1;121(3):851-65

Mesodermal cell/mesoblast sarcoma Mesodermal cell/mesoblast gamma-radiation

29.4

References: Zhao R, J Clin Invest 2011 Mar 1;121(3):851-65

Ovary cyst - epithelial Ovary gamma-radiation

0

References: Zhao R, J Clin Invest 2011 Mar 1;121(3):851-65

Uterus - Endometrium polyp Uterus - Endometrium gamma-radiation

0

References: Zhao R, J Clin Invest 2011 Mar 1;121(3):851-65

(Unspecified organ) carcinoma - serous (Unspecified organ) gamma-radiation

0

References: Zhao R, J Clin Invest 2011 Mar 1;121(3):851-65

(Unspecified organ) cyst - epithelial (Unspecified organ) gamma-radiation

0

References: Zhao R, J Clin Invest 2011 Mar 1;121(3):851-65

(Unspecified organ) hamartoma (Unspecified organ) gamma-radiation

0

References: Zhao R, J Clin Invest 2011 Mar 1;121(3):851-65

(Unspecified organ) tumor (Unspecified organ) gamma-radiation

100

References: Zhao R, J Clin Invest 2011 Mar 1;121(3):851-65