Strain SummaryB6;129-Cops6Gt(RRI087)Byg/+ Trp53tm1Glo/+

Strain Name

B6;129-Cops6Gt(RRI087)Byg/+ Trp53tm1Glo/+

Strain Type(s)

gene trapped  •  targeted mutation (knock-in)

Strain Synonym(s)

Csn6+/-p53+/-

Description

Double heterozygous mice. The genetic background of these mice was a mixture of C57BL/6J and 129 (129P2/OlaHsd and 129S7/SvEvBrd-Hprt+).

Strain Genetics

Cops6Gt(RRI087)Byg / Cops6+
Trp53tm1Glo / Trp53+

Models

11 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Blood vessel tumor - benign Blood vessel gamma-radiation

6.25

References: Zhao R, J Clin Invest 2011 Mar 1;121(3):851-65

Intestine - Small Intestine adenoma Intestine - Small Intestine gamma-radiation

6.25

References: Zhao R, J Clin Invest 2011 Mar 1;121(3):851-65

Leukocyte lymphoma - high-grade Leukocyte gamma-radiation

50

References: Zhao R, J Clin Invest 2011 Mar 1;121(3):851-65

Leukocyte lymphoma - low-grade Leukocyte gamma-radiation

18.75

References: Zhao R, J Clin Invest 2011 Mar 1;121(3):851-65

Lung carcinoma - neuroendocrine Lung gamma-radiation

6.25

References: Zhao R, J Clin Invest 2011 Mar 1;121(3):851-65

Mesodermal cell/mesoblast sarcoma Mesodermal cell/mesoblast gamma-radiation

12.5

References: Zhao R, J Clin Invest 2011 Mar 1;121(3):851-65

Ovary cyst - epithelial Ovary gamma-radiation

0

References: Zhao R, J Clin Invest 2011 Mar 1;121(3):851-65

Uterus - Endometrium polyp Uterus - Endometrium gamma-radiation

0

References: Zhao R, J Clin Invest 2011 Mar 1;121(3):851-65

(Unspecified organ) carcinoma - serous (Unspecified organ) gamma-radiation

0

References: Zhao R, J Clin Invest 2011 Mar 1;121(3):851-65

(Unspecified organ) cyst - epithelial (Unspecified organ) gamma-radiation

0

References: Zhao R, J Clin Invest 2011 Mar 1;121(3):851-65

(Unspecified organ) hamartoma (Unspecified organ) gamma-radiation

0

References: Zhao R, J Clin Invest 2011 Mar 1;121(3):851-65