Strain SummarySTOCK Ptentm2Mak Stk11tm1Keis Tg(Cyp1a1-cre/ERT)1Dwi

Strain Name

STOCK Ptentm2Mak Stk11tm1Keis Tg(Cyp1a1-cre/ERT)1Dwi

Strain Type(s)

targeted mutation (conditional)  •  transgenic

Strain Synonym(s)

AhCreER+ Lkb1fl/fl Ptenfl/fl  •  Cre+ Ptenfl/fl Lkb1fl/fl  •  Lkb1/Pten-deficient

Description

Compound mutant mice. The genetic background of these mice was stated to be a mixture of C57BL/6J, 129P2/OlaHsd, and C3H. It may have also contained some CBA and/or other strain(s).

Strain Genetics

Tg(Cyp1a1-cre/ERT)1Dwi
Tg(Cyp1a1-cre/ERT)1Dwi

Models

4 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Urinary bladder hyperplasia Urinary bladder tamoxifen (For inducing expression from mutant alleles)   ⋅   beta-naphthoflavone (betaNF)

very high

References: Shorning BY, PLoS One 2011;6(1):e16209

2 pathology image(s)

Urinary bladder hyperplasia Urinary bladder tamoxifen (For inducing expression from mutant alleles)   ⋅   beta-naphthoflavone (betaNF)   ⋅   rapamycin

0

References: Shorning BY, PLoS One 2011;6(1):e16209

1 pathology image(s)

Urinary bladder metaplasia - squamous Urinary bladder tamoxifen (For inducing expression from mutant alleles)   ⋅   beta-naphthoflavone (betaNF)

observed

References: Shorning BY, PLoS One 2011;6(1):e16209

1 pathology image(s)

Urinary bladder tumor - papillary Urinary bladder tamoxifen (For inducing expression from mutant alleles)   ⋅   beta-naphthoflavone (betaNF)

observed

References: Shorning BY, PLoS One 2011;6(1):e16209

2 pathology image(s)