Strain SummaryC3B6F1-Ptch1tm1Zim/+

Strain Name

C3B6F1-Ptch1tm1Zim/+

Strain Type(s)

hybrid  •  targeted mutation (knockout)

Strain Synonym(s)

Ptch1+/-

Description

Heterozygous mice. The genetic background of these mice was (C3H/He x C57BL/6)F1 with some contribution from 129/Sv likely around the knockout allele.

Strain Genetics

Ptch1tm1Zim / Ptch1+

Models

9 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
CNS - Brain - Cerebellum medulloblastoma CNS - Brain - Cerebellum

52.2

22.9

34.5

References: Ishida Y, Carcinogenesis 2010 Sep;31(9):1694-701

CNS - Brain - Cerebellum medulloblastoma CNS - Brain - Cerebellum X-radiation

47.1 - 100

40 - 100

52.5 - 100

References: Ishida Y, Carcinogenesis 2010 Sep;31(9):1694-701

CNS - Brain - Cerebellum normal tissue (control) CNS - Brain - Cerebellum

not applicable

References: Ishida Y, Carcinogenesis 2010 Sep;31(9):1694-701

Ear - Outer ear normal tissue (control) Ear - Outer ear

not applicable

References: Ishida Y, Carcinogenesis 2010 Sep;31(9):1694-701

Ear - Outer ear normal tissue (control) Ear - Outer ear X-radiation

not applicable

not applicable

References: Ishida Y, Carcinogenesis 2010 Sep;31(9):1694-701

Muscle - Striated - Skeletal rhabdomyosarcoma Muscle - Striated - Skeletal

6.9

References: Ishida Y, Carcinogenesis 2010 Sep;31(9):1694-701

Muscle - Striated - Skeletal rhabdomyosarcoma Muscle - Striated - Skeletal X-radiation

0 - 9.5

References: Ishida Y, Carcinogenesis 2010 Sep;31(9):1694-701

(Unspecified organ) lesion (Unspecified organ)

6.9

References: Ishida Y, Carcinogenesis 2010 Sep;31(9):1694-701

(Unspecified organ) lesion (Unspecified organ) X-radiation

0 - 21.1

References: Ishida Y, Carcinogenesis 2010 Sep;31(9):1694-701