Strain SummarySTOCK Apctm1Rak Rb1tm2Brn/+

Strain Name

STOCK Apctm1Rak Rb1tm2Brn/+

Strain Type(s)

targeted mutation (conditional)  •  targeted mutation (knockout)

Strain Synonym(s)

Rb-/-, VCnegative, Apc+/-

Description

These mice were heterozygous for Rb1tm2Brn, homozygous for Apctm1Rak, and carried the transgene. This STOCK genetic background was a mixture of 129 (substrain unspecified), 129P2/OlaHsd, FVB, C57BL/6, and DBA/2.

Strain Genetics

Apctm1Rak / Apc+

Models

13 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Gastrointestinal tract adenocarcinoma Gastrointestinal tract

33.33

References: Kucherlapati MH, Proc Natl Acad Sci U S A 2008 Oct 7;105(40):15493-8

Gastrointestinal tract adenoma - villous Gastrointestinal tract

22.22

References: Kucherlapati MH, Proc Natl Acad Sci U S A 2008 Oct 7;105(40):15493-8

Gastrointestinal tract tumor Gastrointestinal tract

88.89

References: Kucherlapati MH, Proc Natl Acad Sci U S A 2008 Oct 7;105(40):15493-8

Intestine - Large Intestine - Cecum tumor Intestine - Large Intestine - Cecum

88.89

References: Kucherlapati MH, Proc Natl Acad Sci U S A 2008 Oct 7;105(40):15493-8

Intestine - Large Intestine - Colon - Distal tumor Intestine - Large Intestine - Colon - Distal

22.22

References: Kucherlapati MH, Proc Natl Acad Sci U S A 2008 Oct 7;105(40):15493-8

Intestine - Large Intestine - Colon - Proximal tumor Intestine - Large Intestine - Colon - Proximal

0

References: Kucherlapati MH, Proc Natl Acad Sci U S A 2008 Oct 7;105(40):15493-8

Intestine - Large Intestine adenocarcinoma Intestine - Large Intestine

0

References: Kucherlapati MH, Proc Natl Acad Sci U S A 2008 Oct 7;105(40):15493-8

Intestine - Large Intestine adenoma - villous Intestine - Large Intestine

11.11

References: Kucherlapati MH, Proc Natl Acad Sci U S A 2008 Oct 7;105(40):15493-8

Intestine - Large Intestine tumor Intestine - Large Intestine

22.22

References: Kucherlapati MH, Proc Natl Acad Sci U S A 2008 Oct 7;105(40):15493-8

Intestine - Small Intestine adenocarcinoma Intestine - Small Intestine

33.33

References: Kucherlapati MH, Proc Natl Acad Sci U S A 2008 Oct 7;105(40):15493-8

Intestine - Small Intestine adenoma - villous Intestine - Small Intestine

11.11

References: Kucherlapati MH, Proc Natl Acad Sci U S A 2008 Oct 7;105(40):15493-8

Intestine - Small Intestine tumor Intestine - Small Intestine

88.89

References: Kucherlapati MH, Proc Natl Acad Sci U S A 2008 Oct 7;105(40):15493-8

Stomach tumor Stomach

44.44

References: Kucherlapati MH, Proc Natl Acad Sci U S A 2008 Oct 7;105(40):15493-8