Strain SummaryC57BL/6-Cbltm2Hua Cblbtm1Hua Tg(MMTV-cre)4Mam

Strain Name

C57BL/6-Cbltm2Hua Cblbtm1Hua Tg(MMTV-cre)4Mam

Strain Type(s)

targeted mutation (conditional)  •  targeted mutation (knockout)  •  transgenic

Strain Synonym(s)

MMTV-Cre; Cblflox/flox; Cblbdel/del

Description

Mice were homozygous for Cbltm2Hua and Cblbtm1Hua and carried the Tg(MMTV-cre)4Mam transgene. Background was C57BL/6 (backcrossed at least 5 generations) with contributions from 129P2/OlaHsd, unspecified 129, and FVB.

Strain Genetics

Tg(MMTV-cre)4Mam

Models

2 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Leukocyte - Myelocyte (Granulocyte) hyperplasia Leukocyte - Myelocyte (Granulocyte)

observed

References: Naramura M, Proc Natl Acad Sci U S A 2010 Sep 14;107(37):16274-9

2 pathology image(s)

Leukocyte - Myelocyte (Granulocyte) leukemia - myelocytic Leukocyte - Myelocyte (Granulocyte)

observed

References: Naramura M, Proc Natl Acad Sci U S A 2010 Sep 14;107(37):16274-9

2 pathology image(s)