Mouse Tumor Biology Database (MTB)
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Last Database Update
MTB 3.0
HelpHelp and Documentation Strain Tumor Overview
Collapsed View
C57BL/6-Mdm2tm4.1Glo Trp53tm3.1Glo/+
Strain Synonyms Mdm2SNP309T/T p53515A/+
Strain Note: Compound mutant mice. These mice were the product of crosses between mutant mice which had each been backcrossed onto C57BL/6. 129S6/SvEvTac and 129S7/SvEvBrd-Hprt+-derived ES cells were used to generate the mutant alleles.
Strain Tumor Overview Expanded View
Tumors 22 unique tumor types displayed.

A tumor group is a set of tumors that share the same tumor name, organ(s) affected, and treatment type.

Tumor Name Organ(s) Affected Treatment Type Number of
Tumor Group Records
Frequency Range
Adipose tissue lipoma Adipose tissue None (spontaneous) 1 1.2
Blood vessel hemangiosarcoma Ovary None (spontaneous) 1 0
Bone osteosarcoma Bone None (spontaneous) 2 7.3
Connective tissue - Cartilage chondrosarcoma Connective tissue - Cartilage None (spontaneous) 1 0
Connective tissue - Fibroblast fibrosarcoma Connective tissue - Fibroblast None (spontaneous) 1 2.4
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Leukocyte - Monocyte - Macrophage - Histiocyte None (spontaneous) 1 6.1
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytoma Leukocyte - Monocyte - Macrophage - Histiocyte None (spontaneous) 1 0
Leukocyte lymphoma Leukocyte None (spontaneous) 1 1.2
Liver hepatocellular adenocarcinoma Liver None (spontaneous) 1 2.4
Liver hepatocellular adenoma Liver None (spontaneous) 1 0
Lung adenoma Lung None (spontaneous) 1 0
Mammary gland adenocarcinoma Mammary gland None (spontaneous) 1 0
Mesodermal cell/mesoblast sarcoma Mesodermal cell/mesoblast None (spontaneous) 2 2.4 - 18
Mesodermal cell/mesoblast sarcoma - pleomorphic Mesodermal cell/mesoblast None (spontaneous) 1 0
Mesodermal cell/mesoblast sarcoma - spindle cell Mesodermal cell/mesoblast None (spontaneous) 1 1.2
Muscle - Smooth leiomyosarcoma Muscle - Smooth None (spontaneous) 1 0
Salivary gland carcinoma Salivary gland None (spontaneous) 1 0
(Unspecified organ) adenocarcinoma (Unspecified organ) None (spontaneous) 1 3.7
(Unspecified organ) carcinoma (Unspecified organ) None (spontaneous) 1 1.2
(Unspecified organ) squamous cell carcinoma (Unspecified organ) None (spontaneous) 1 1.2
(Unspecified organ) squamous cell papilloma (Unspecified organ) None (spontaneous) 1 0
(Unspecified organ) tumor (Unspecified organ) None (spontaneous) 1 28