Strain Summary[not specified]-Krastm4Tyj/+ Tg(CAG-Bgeo/GFP)21Lbe Tg(Pdx1-cre)6Tuv Trp53tm2Glo/+

Strain Name

[not specified]-Krastm4Tyj/+ Tg(CAG-Bgeo/GFP)21Lbe Tg(Pdx1-cre)6Tuv Trp53tm2Glo/+

Strain Type(s)

targeted mutation (conditional)  •  transgenic

Strain Synonym(s)

KP21C  •  [not specified]-Krastm4Tyj/+ Tg(CAG-Bgeo/GFP)21Lbe Tg(Ipf1-cre)1Tuv Trp53tm2Glo/+  •  [not specified]-Krastm4Tyj/+ Tg(CAG-Bgeo/GFP)21Lbe Tg(Ipf1-cre)6Tuv Trp53tm2Glo/+  •  [not specified]-Krastm4Tyj/+ Tg(CAG-Bgeo/GFP)21Lbe Tg(Pdx1-cre)6Tuv Trp53tm2Glo/+  •  Pdx1-Cre-GFP, LSL-KrasG12D/+, LSL-Trp53R172P/+

Description

Background was not specified but contained at least some FVB/N and multiple 129 substrains. Mice were heterozygous for Krastm4Tyj and Trp53tm2Glo and carried the Tg(Pdx1-cre)6Tuv and Tg(CAG-Bgeo/GFP)21Lbe transgenes.

Strain Genetics

Tg(CAG-Bgeo/GFP)21Lbe
Tg(CAG-Bgeo/GFP)21Lbe
Krastm4Tyj / Kras+
Trp53tm2Glo / Trp53+
Tg(CAG-Bgeo/GFP)21Lbe
Tg(Pdx1-cre)6Tuv

Models

2 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Pancreas - Duct pancreatic intraepithelial neoplasia (PanIN) Pancreas - Duct

observed

References: Morton JP, Proc Natl Acad Sci U S A 2010 Jan 5;107(1):246-51

Pancreas adenocarcinoma - ductal Pancreas

0

References: Morton JP, Proc Natl Acad Sci U S A 2010 Jan 5;107(1):246-51

3 pathology image(s)