Strain Summary[not specified]-Smad4tm1Cxd/+

Strain Name

[not specified]-Smad4tm1Cxd/+

Strain Type(s)

targeted mutation (knockout)

Strain Synonym(s)

Smad48+/-  •  Smad4ex8/+  •  smad4+/-  •  Smad4+/-

Description

Heterozygous mice. The genetic background of these mice was not specified but included Black Swiss and 129S6/SvEvTac.

Strain Genetics

Smad4tm1Cxd / Smad4+

Models

20 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Eye - Harderian gland dysplasia Eye - Harderian gland

6.25

References: Redman RS, J Oral Pathol Med 2005 Jan;34(1):23-9

Eye - Harderian gland hyperplasia Eye - Harderian gland

6.25

References: Redman RS, J Oral Pathol Med 2005 Jan;34(1):23-9

Forestomach squamous cell carcinoma Forestomach

6.25

References: Redman RS, J Oral Pathol Med 2005 Jan;34(1):23-9

Intestine - Small Intestine - Brunner's gland hyperplasia Intestine - Small Intestine - Brunner's gland

6.25

References: Redman RS, J Oral Pathol Med 2005 Jan;34(1):23-9

Intestine - Small Intestine - Duodenum adenoma - tubular Intestine - Small Intestine - Duodenum

25

References: Redman RS, J Oral Pathol Med 2005 Jan;34(1):23-9

Intestine - Small Intestine - Duodenum dysplasia Intestine - Small Intestine - Duodenum

observed

References: Redman RS, J Oral Pathol Med 2005 Jan;34(1):23-9

Intestine - Small Intestine - Duodenum hyperplasia Intestine - Small Intestine - Duodenum

19

References: Redman RS, J Oral Pathol Med 2005 Jan;34(1):23-9

Leukocyte - Lymphocyte - B-lymphocyte - Plasma cell lymphoma - large cell Lymph node

6.25

References: Redman RS, J Oral Pathol Med 2005 Jan;34(1):23-9

Mouth - Oral mucosa dysplasia Mouth - Oral mucosa

observed

References: Redman RS, J Oral Pathol Med 2005 Jan;34(1):23-9

Mouth - Oral mucosa hyperplasia Mouth - Oral mucosa

observed

References: Redman RS, J Oral Pathol Med 2005 Jan;34(1):23-9

Oral cavity squamous cell carcinoma Oral cavity

19

References: Redman RS, J Oral Pathol Med 2005 Jan;34(1):23-9

Salivary gland - Salivary duct - Parotid metaplasia - squamous Salivary gland - Salivary duct - Parotid

6.25

References: Redman RS, J Oral Pathol Med 2005 Jan;34(1):23-9

Salivary gland - Submandibular adenoma Salivary gland - Submandibular

0

References: Redman RS, J Oral Pathol Med 2005 Jan;34(1):23-9

Salivary gland - Submandibular dysplasia Salivary gland - Submandibular

0

References: Redman RS, J Oral Pathol Med 2005 Jan;34(1):23-9

Skin squamous cell carcinoma Ear - Outer ear

6.25

References: Redman RS, J Oral Pathol Med 2005 Jan;34(1):23-9

Stomach - Glandular adenocarcinoma Stomach - Glandular

6.25

References: Redman RS, J Oral Pathol Med 2005 Jan;34(1):23-9

Stomach - Glandular adenoma - tubular Stomach - Glandular

25

References: Redman RS, J Oral Pathol Med 2005 Jan;34(1):23-9

Stomach - Glandular dysplasia Stomach - Glandular

observed

References: Redman RS, J Oral Pathol Med 2005 Jan;34(1):23-9

Stomach - Glandular hyperplasia Stomach - Glandular

37.5

References: Redman RS, J Oral Pathol Med 2005 Jan;34(1):23-9

(Unspecified organ) fibromyxolipoma Leg

6.25

References: Redman RS, J Oral Pathol Med 2005 Jan;34(1):23-9