Mouse Tumor Biology Database (MTB)
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Last Database Update
MTB 3.0
HelpHelp and Documentation Strain Tumor Overview
Collapsed View
Strain Synonyms p53-/-  •  p53-/-  •  Trp53-/-  •  p53-/-
Strain Note: Homozygous mice. These mice have been backcrossed to C57BL/6. The mutation was generated on a 129S7/SvEvBrd-Hprt+ genetic background.
Strain Tumor Overview Expanded View
Tumors 14 unique tumor types displayed.

A tumor group is a set of tumors that share the same tumor name, organ(s) affected, and treatment type.

Tumor Name Organ(s) Affected Treatment Type Number of
Tumor Group Records
Frequency Range
Bone osteosarcoma Bone None (spontaneous) 1 0
Bone osteosarcoma Bone Other 1 observed
Connective tissue - Fibroblast fibrosarcoma Connective tissue - Fibroblast None (spontaneous) 1 3.2
Leukocyte lymphoma Leukocyte None (spontaneous) 2 35 - 68
Leukocyte lymphoma Thymus None (spontaneous) 1 32
Leukocyte lymphoma Leukocyte Other 1 observed
Liver hyperplasia Liver Other 1 observed
Mesodermal cell/mesoblast sarcoma Mesodermal cell/mesoblast None (spontaneous) 1 16
Mesodermal cell/mesoblast sarcoma - poorly differentiated Mesodermal cell/mesoblast None (spontaneous) 1 observed
Mesodermal cell/mesoblast sarcoma - well differentiated Mesodermal cell/mesoblast None (spontaneous) 1 observed
Salivary gland hyperplasia Salivary gland Other 1 observed
(Unspecified organ) angiosarcoma (Unspecified organ) None (spontaneous) 1 3.2
(Unspecified organ) histiocytoma - fibrous - malignant (Unspecified organ) None (spontaneous) 1 observed
(Unspecified organ) tumor (Unspecified organ) None (spontaneous) 2 84 - 100