Strain SummaryB6;129-Trp53tm1Wahl/+

Strain Name

B6;129-Trp53tm1Wahl/+

Strain Type(s)

targeted mutation (knock-in)

Strain Synonym(s)

p53+/QSval  •  Trp53+/QSval  •  p53+/QSval

Description

Heterozygous mice. The genetic background of these mice was stated to be on a ">=75%" C57BL/6 genetic background. This background also contained some 129S4/SvJae and possibly some other strain or strains.

Strain Genetics

Trp53tm1Wahl / Trp53+

Models

18 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Abdominal wall tumor - anaplastic Abdominal wall

0.5

References: Nister M, Oncogene 2005 May 19;24(22):3563-73

Adipose tissue liposarcoma Adipose tissue

observed

References: Nister M, Oncogene 2005 May 19;24(22):3563-73

Bone osteosarcoma Bone

7.5

References: Nister M, Oncogene 2005 May 19;24(22):3563-73

CNS - Brain glioma - malignant CNS - Brain

0.5

References: Nister M, Oncogene 2005 May 19;24(22):3563-73

Connective tissue - Fibroblast fibrosarcoma Connective tissue - Fibroblast

3.5

References: Nister M, Oncogene 2005 May 19;24(22):3563-73

Leukocyte lymphoma Leukocyte

9.0 - 12

References: Nister M, Oncogene 2005 May 19;24(22):3563-73

Leukocyte lymphoma Thymus

3.5

References: Nister M, Oncogene 2005 May 19;24(22):3563-73

Liver adenocarcinoma Liver

0.5

References: Nister M, Oncogene 2005 May 19;24(22):3563-73

Liver carcinoma Liver

0.5

References: Nister M, Oncogene 2005 May 19;24(22):3563-73

Lung carcinoma Lung

0.5

References: Nister M, Oncogene 2005 May 19;24(22):3563-73

Mesodermal cell/mesoblast sarcoma Mesodermal cell/mesoblast

15

References: Nister M, Oncogene 2005 May 19;24(22):3563-73

Skin carcinoma Skin

1.0

References: Nister M, Oncogene 2005 May 19;24(22):3563-73

Skin squamous cell carcinoma Skin

1.5

References: Nister M, Oncogene 2005 May 19;24(22):3563-73

Skin squamous cell papilloma Skin

0.5

References: Nister M, Oncogene 2005 May 19;24(22):3563-73

Testis - Germ cell teratoma Testis - Germ cell

0.5

References: Nister M, Oncogene 2005 May 19;24(22):3563-73

(Unspecified organ) angiosarcoma (Unspecified organ)

1.5

References: Nister M, Oncogene 2005 May 19;24(22):3563-73

(Unspecified organ) tumor (Unspecified organ)

34 - 90

References: Nister M, Oncogene 2005 May 19;24(22):3563-73

(Unspecified organ) tumor - anaplastic (Unspecified organ)

0.5

References: Nister M, Oncogene 2005 May 19;24(22):3563-73