Mouse Tumor Biology Database (MTB)
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Last Database Update
2020-07-12
MTB 3.0
 
HelpHelp and Documentation Strain Tumor Overview
Collapsed View
 
Strain
B6.129-Trp53tm1Tyj/+ Xpatm1Hvs
Strain Synonyms C57BL/6 Xpa/p53  •  combined Xpa homozygous and p53 heterozygous knockout  •  Xpa/p53
Strain Note: Mice were heterozygous for the Trp53 mutation and homozygous for the Xpa mutation. The genetic background of these mice is backcrossed C57BL/6 (most likely C57BL/6J).
Strain Tumor Overview Expanded View
Tumors 34 unique tumor types displayed.

A tumor group is a set of tumors that share the same tumor name, organ(s) affected, and treatment type.

Tumor Name Organ(s) Affected Treatment Type Number of
Tumor Group Records
Frequency Range
Adrenal gland - Medulla pheochromocytoma Adrenal gland - Medulla None (spontaneous) 2 0
Adrenal gland - Medulla pheochromocytoma Adrenal gland - Medulla Hormone 2 0 - 6.7
Adrenal gland - Subcapsular cell hyperplasia Adrenal gland - Subcapsular cell None (spontaneous) 2 33 - 100
Adrenal gland - Subcapsular cell hyperplasia Adrenal gland - Subcapsular cell Hormone 2 93
Bone lesion Bone - Sternum None (spontaneous) 2 0
Bone lesion Bone - Femur None (spontaneous) 2 0 - 6.7
Bone lesion Bone - Sternum Hormone 2 53 - 60
Bone lesion Bone - Femur Hormone 2 80
Bone osteosarcoma Bone None (spontaneous) 2 0
Bone osteosarcoma Bone Hormone 5 13 - 33
Bone osteosarcoma Leg Hormone 1 27
CNS - Brain - Cerebrum glioma CNS - Brain - Cerebrum None (spontaneous) 2 0
CNS - Brain - Cerebrum glioma CNS - Brain - Cerebrum Hormone 2 0 - 6.7
Connective tissue - Fibroblast fibrosarcoma Uterus - Cervix None (spontaneous) 1 0
Connective tissue - Fibroblast fibrosarcoma Uterus - Cervix Hormone 1 6.7
Leukocyte - Lymphocyte - T-lymphocyte lymphoma Leukocyte - Lymphocyte - T-lymphocyte None (spontaneous) 2 0
Leukocyte - Lymphocyte - T-lymphocyte lymphoma Leukocyte - Lymphocyte - T-lymphocyte Hormone 3 0 - 13
Mammary gland adenocarcinoma Mammary gland None (spontaneous) 1 6.7
Mammary gland adenocarcinoma Mammary gland Hormone 1 0
Mammary gland hyperplasia - focal Mammary gland None (spontaneous) 1 0
Mammary gland hyperplasia - focal Mammary gland Hormone 1 67
Pituitary gland - Pars distalis hyperplasia Pituitary gland - Pars distalis None (spontaneous) 2 0
Pituitary gland - Pars distalis hyperplasia Pituitary gland - Pars distalis Hormone 2 73
Pituitary gland - Pars intermedia hyperplasia Pituitary gland - Pars intermedia None (spontaneous) 2 0
Pituitary gland - Pars intermedia hyperplasia Pituitary gland - Pars intermedia Hormone 2 33 - 47
Pituitary gland adenoma Pituitary gland None (spontaneous) 2 0
Pituitary gland adenoma Pituitary gland Hormone 2 13
Prostate gland - Anterior lobe metaplasia - squamous Prostate gland - Anterior lobe None (spontaneous) 1 0
Prostate gland - Anterior lobe metaplasia - squamous Prostate gland - Anterior lobe Hormone 1 40
Testis - Leydig cell (Interstitial cell) adenoma Testis - Leydig cell (Interstitial cell) None (spontaneous) 1 0
Testis - Leydig cell (Interstitial cell) adenoma Testis - Leydig cell (Interstitial cell) Hormone 1 27
Testis - Leydig cell (Interstitial cell) hyperplasia Testis - Leydig cell (Interstitial cell) None (spontaneous) 1 0
Testis - Leydig cell (Interstitial cell) hyperplasia Testis - Leydig cell (Interstitial cell) Hormone 1 60
Uterus - Uterine gland hyperplasia Uterus - Uterine gland Hormone 1 observed