Mouse Tumor Biology Database (MTB)
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Last Database Update
2020-07-12
MTB 3.0
 
HelpHelp and Documentation Strain Tumor Overview
Collapsed View
 
Strain
B6.129P2-Xpatm1Hvs
Strain Synonyms C57BL/6 Xpa  •  C57Bl/6J-TgH(XPAIm)55Cmg  •  Xpa  •  Xpa homozygous knockout  •  Xpa-/-  •  XPA
Strain Note: Homozygous mice. The genetic background of these mice is backcrossed C57BL/6J with the targeted mutation having been generated on a 129P2/OlaHsd background.
Strain Tumor Overview Expanded View
Tumors 103 unique tumor types displayed.

A tumor group is a set of tumors that share the same tumor name, organ(s) affected, and treatment type.

Tumor Name Organ(s) Affected Treatment Type Number of
Tumor Group Records
Frequency Range
Adipose tissue lipoma Abdominal cavity None (spontaneous) 2 0
Adipose tissue lipoma CNS - Brain None (spontaneous) 2 0
Adipose tissue lipoma CNS - Brain Hormone 2 0
Adrenal gland - Cortex adenoma Adrenal gland - Cortex None (spontaneous) 2 0 - 2.2
Adrenal gland - Medulla pheochromocytoma Adrenal gland - Medulla None (spontaneous) 6 0 - 1.1
Adrenal gland - Medulla pheochromocytoma Adrenal gland - Medulla Hormone 12 0
Adrenal gland - Subcapsular cell hyperplasia Adrenal gland - Subcapsular cell None (spontaneous) 2 6.7 - 100
Adrenal gland - Subcapsular cell hyperplasia Adrenal gland - Subcapsular cell Hormone 6 60 - 100
Blood vessel hemangiosarcoma Blood vessel None (spontaneous) 2 0 - 0.6
Bone lesion Bone - Sternum None (spontaneous) 2 0 - 6.7
Bone lesion Bone - Femur None (spontaneous) 2 0
Bone lesion Bone - Sternum Hormone 6 0 - 60
Bone lesion Bone - Femur Hormone 6 0 - 100
Bone lesion - fibro-osseous Bone None (spontaneous) 2 0
Bone lesion - fibro-osseous Bone Hormone 2 46.7 - 100
Bone osteosarcoma Bone None (spontaneous) 8 0 - 0.6
Bone osteosarcoma Bone Hormone 13 0 - 6.7
Bone osteosarcoma Bone - Sternum Hormone 2 6.7
CNS - Brain - Cerebrum glioma CNS - Brain - Cerebrum None (spontaneous) 2 0
CNS - Brain - Cerebrum glioma CNS - Brain - Cerebrum Hormone 6 0
CNS - Brain glioma CNS - Brain None (spontaneous) 2 0
CNS - Brain glioma CNS - Brain Hormone 6 0
Connective tissue - Fibroblast fibrosarcoma Uterus - Cervix None (spontaneous) 2 0
Connective tissue - Fibroblast fibrosarcoma Uterus - Cervix Hormone 6 0
Connective tissue - Fibroblast fibrosarcoma Skin None (spontaneous) 2 0 - 0.6
Forestomach papilloma Forestomach Chemical/Drug 2 13
Forestomach squamous cell carcinoma Forestomach Chemical/Drug 1 6.7
Forestomach tumor Forestomach Chemical/Drug 8 0 - 40
Gallbladder papilloma Gallbladder Chemical/Drug 2 0 - 26.7
Intestine - Large Intestine - Cecum adenoma Intestine - Large Intestine - Cecum Chemical/Drug 1 6.7
Intestine - Small Intestine - Duodenum adenocarcinoma Intestine - Small Intestine - Duodenum Chemical/Drug 1 6.7
Intestine - Small Intestine - Duodenum adenoma Intestine - Small Intestine - Duodenum Chemical/Drug 1 6.7
Intestine - Small Intestine - Ileum adenocarcinoma Intestine - Small Intestine - Ileum Chemical/Drug 1 6.7
Intestine - Small Intestine - Ileum adenoma Intestine - Small Intestine - Ileum Chemical/Drug 1 6.7
Intestine - Small Intestine - Jejunum adenocarcinoma Intestine - Small Intestine - Jejunum Chemical/Drug 2 20
Intestine - Small Intestine - Jejunum adenoma Intestine - Small Intestine - Jejunum Chemical/Drug 1 20
Intestine - Small Intestine adenocarcinoma Intestine - Small Intestine None (spontaneous) 2 0
Intestine - Small Intestine adenocarcinoma Intestine - Small Intestine Chemical/Drug 6 0
Intestine - Small Intestine tumor Intestine - Small Intestine None (spontaneous) 2 0
Intestine tumor Intestine Chemical/Drug 8 0 - 46.7
Kidney hyperplasia Kidney Chemical/Drug 2 observed
Kidney transitional cell carcinoma Kidney Chemical/Drug 5 0 - 6.7
Kidney tumor Kidney Chemical/Drug 2 0
Leukocyte - Lymphocyte - B-lymphocyte lymphoma Leukocyte - Lymphocyte - B-lymphocyte Chemical/Drug 6 13 - 20
Leukocyte - Lymphocyte - T-lymphocyte lymphoma Leukocyte - Lymphocyte - T-lymphocyte None (spontaneous) 2 0
Leukocyte - Lymphocyte - T-lymphocyte lymphoma Leukocyte - Lymphocyte - T-lymphocyte Hormone 7 0 - 6.7
Leukocyte - Lymphocyte - T-lymphocyte lymphoma Leukocyte - Lymphocyte - T-lymphocyte Chemical/Drug 3 6.7
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Leukocyte - Monocyte - Macrophage - Histiocyte None (spontaneous) 2 0 - 0.6
Leukocyte - Myelocyte (Granulocyte) leukemia - myelocytic Leukocyte - Myelocyte (Granulocyte) None (spontaneous) 2 0
Leukocyte - Myelocyte (Granulocyte) leukemia - myelocytic Leukocyte - Myelocyte (Granulocyte) Hormone 2 0
Leukocyte - Myelocyte (Granulocyte) sarcoma - myeloid Leukocyte - Myelocyte (Granulocyte) None (spontaneous) 2 0
Leukocyte lymphoma Leukocyte None (spontaneous) 10 0 - 1.1
Leukocyte lymphoma Leukocyte Chemical/Drug 22 0 - 66.7
Leukocyte lymphoma Leukocyte Hormone 8 0 - 6.7
Liver - Oval cell hyperplasia Liver - Oval cell None (spontaneous) 2 0
Liver - Oval cell hyperplasia Liver - Oval cell Chemical/Drug 6 0 - 26.7
Liver adenoma Liver None (spontaneous) 3 0 - 0.6
Liver hepatocellular adenoma Liver None (spontaneous) 2 0
Liver hepatocellular adenoma Liver Chemical/Drug 6 0 - 40
Liver hepatocellular carcinoma Liver None (spontaneous) 4 0
Liver hepatocellular carcinoma Liver Hormone 2 0
Liver hepatocellular carcinoma Liver Chemical/Drug 6 0 - 6.7
Liver tumor Liver Chemical/Drug 7 0 - 53.3
Lung adenoma Lung None (spontaneous) 4 0 - 6.7
Lung adenoma Lung Hormone 2 0 - 6.7
Mammary gland adenocarcinoma Mammary gland None (spontaneous) 5 0
Mammary gland adenocarcinoma Mammary gland Hormone 9 0
Mammary gland hyperplasia - focal Mammary gland None (spontaneous) 1 0
Mammary gland hyperplasia - focal Mammary gland Hormone 3 0 - 73
Mesodermal cell/mesoblast sarcoma CNS - Brain None (spontaneous) 4 0
Mesodermal cell/mesoblast sarcoma Abdominal cavity None (spontaneous) 4 0
Mesodermal cell/mesoblast sarcoma Skin None (spontaneous) 2 0
Mesodermal cell/mesoblast sarcoma Skin Hormone 2 0
Mesodermal cell/mesoblast sarcoma CNS - Brain Hormone 2 0
Mesodermal cell/mesoblast sarcoma Abdominal cavity Hormone 2 0
Muscle - Smooth leiomyosarcoma Muscle - Smooth None (spontaneous) 2 0
Ovary - Germ cell teratoma CNS - Brain None (spontaneous) 1 0
Ovary - Germ cell teratoma CNS - Brain Hormone 1 0
Ovary - Granulosa cell tumor Ovary - Granulosa cell None (spontaneous) 1 0
Ovary adenoma - tubulostromal Ovary None (spontaneous) 1 0.6
Pituitary gland - Pars distalis hyperplasia Pituitary gland - Pars distalis None (spontaneous) 2 0
Pituitary gland - Pars distalis hyperplasia Pituitary gland - Pars distalis Hormone 6 0 - 87
Pituitary gland - Pars intermedia hyperplasia Pituitary gland - Pars intermedia None (spontaneous) 2 0
Pituitary gland - Pars intermedia hyperplasia Pituitary gland - Pars intermedia Hormone 6 0 - 53
Pituitary gland adenoma Pituitary gland None (spontaneous) 4 0
Pituitary gland adenoma Pituitary gland Hormone 12 0 - 33.3
Placenta - Decidua deciduoma Placenta - Decidua None (spontaneous) 1 0.6
Prostate gland - Anterior lobe metaplasia - squamous Prostate gland - Anterior lobe None (spontaneous) 1 0
Prostate gland - Anterior lobe metaplasia - squamous Prostate gland - Anterior lobe Hormone 3 0 - 60
Testis - Germ cell teratoma CNS - Brain None (spontaneous) 1 0
Testis - Germ cell teratoma CNS - Brain Hormone 1 0
Testis - Leydig cell (Interstitial cell) adenoma Testis - Leydig cell (Interstitial cell) None (spontaneous) 2 0
Testis - Leydig cell (Interstitial cell) adenoma Testis - Leydig cell (Interstitial cell) Hormone 6 0 - 26.7
Testis - Leydig cell (Interstitial cell) hyperplasia Testis - Leydig cell (Interstitial cell) None (spontaneous) 1 0
Testis - Leydig cell (Interstitial cell) hyperplasia Testis - Leydig cell (Interstitial cell) Hormone 3 0 - 67
Thymus thymoma Thymus None (spontaneous) 2 0
Thyroid gland - Follicular cell adenoma Thyroid gland - Follicular cell None (spontaneous) 2 0
Urinary bladder preneoplastic lesion Urinary bladder Chemical/Drug 1 observed
Urinary bladder tumor Urinary bladder Chemical/Drug 7 0 - 20
Uterus - Uterine gland hyperplasia Uterus - Uterine gland Hormone 1 observed
(Unspecified organ) tumor (Unspecified organ) None (spontaneous) 13 0 - 7.2
(Unspecified organ) tumor (Unspecified organ) Chemical/Drug 15 0 - 93.3
(Unspecified organ) tumor (Unspecified organ) Hormone 6 0 - 53.3