Strain Summary[not specified]-Cdkn2atm4Rdp Krastm4Tyj/+ Tg(Pdx1-cre)89.1Dam

Strain Name

[not specified]-Cdkn2atm4Rdp Krastm4Tyj/+ Tg(Pdx1-cre)89.1Dam

Strain Type(s)

targeted mutation (conditional)  •  transgenic

Strain Synonym(s)

Ink/Arf L/L  •  Pdx1-Cre; LSL-KrasG12D; Ink4a/Arflox/lox

Description

Compound mutant mice. The genetic background was not specified but included C57BL/6, CBA, and likely some FVB/N.

Strain Genetics

Tg(Pdx1-cre)89.1Dam
Krastm4Tyj / Kras+

Models

4 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Pancreas - Duct pancreatic intraepithelial neoplasia (PanIN) Pancreas - Duct

100

References: Aguirre AJ, Genes Dev 2003 Dec 15;17(24):3112-26

Pancreas - Duct tumor - malignant Pancreas - Duct

33

References: Aguirre AJ, Genes Dev 2003 Dec 15;17(24):3112-26

Pancreas adenocarcinoma - ductal Pancreas

observed - 100

References: Aguirre AJ, Genes Dev 2003 Dec 15;17(24):3112-26

Sites of Metastasis: not Lung , Liver , Lymph node

Pancreas pancreatic intraepithelial neoplasia (PanIN) Pancreas

100

References: Aguirre AJ, Genes Dev 2003 Dec 15;17(24):3112-26