Strain SummaryB6;129-Trp53tm1Brd/Trp53tm1Snj

Strain Name

B6;129-Trp53tm1Brd/Trp53tm1Snj

Strain Type(s)

targeted mutation (knock-in)  •  targeted mutation (knockout)

Strain Synonym(s)

p53S18A/-  •  p53S18A/-

Description

Targeted mutant mice. The genetic background of these mice was a mixture of C57BL/6 and "129/Sv" (substrain not specified but it included at least some 129S4/SvJae and some 129S7/SvEvBrd-Hprt1+).

Strain Genetics

Trp53tm1Brd / Trp53tm1Snj

Models

13 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Blood vessel hemangiosarcoma Blood vessel

0

References: Armata HL, Cancer Res 2007 Dec 15;67(24):11696-703

Bone osteosarcoma Bone

12.5

References: Armata HL, Cancer Res 2007 Dec 15;67(24):11696-703

CNS - Brain oligodendroma CNS - Brain

0

References: Armata HL, Cancer Res 2007 Dec 15;67(24):11696-703

Connective tissue - Fibroblast fibrosarcoma Connective tissue - Fibroblast

6.25

References: Armata HL, Cancer Res 2007 Dec 15;67(24):11696-703

Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Liver

6.25

References: Armata HL, Cancer Res 2007 Dec 15;67(24):11696-703

Leukocyte - Myelocyte (Granulocyte) leukemia - myelocytic Leukocyte - Myelocyte (Granulocyte)

6.25

References: Armata HL, Cancer Res 2007 Dec 15;67(24):11696-703

Leukocyte lymphoma Leukocyte

19

References: Armata HL, Cancer Res 2007 Dec 15;67(24):11696-703

Mesodermal cell/mesoblast myxosarcoma Muscle - Striated - Skeletal

6.25

References: Armata HL, Cancer Res 2007 Dec 15;67(24):11696-703

Mesodermal cell/mesoblast sarcoma - unclassified Mesodermal cell/mesoblast

6.25

References: Armata HL, Cancer Res 2007 Dec 15;67(24):11696-703

Muscle - Smooth leiomyosarcoma Muscle - Smooth

0

References: Armata HL, Cancer Res 2007 Dec 15;67(24):11696-703

(Unspecified organ) adenoma (Unspecified organ)

0

References: Armata HL, Cancer Res 2007 Dec 15;67(24):11696-703

(Unspecified organ) carcinoma (Unspecified organ)

12.5

References: Armata HL, Cancer Res 2007 Dec 15;67(24):11696-703

(Unspecified organ) tumor (Unspecified organ)

69

References: Armata HL, Cancer Res 2007 Dec 15;67(24):11696-703