Strain Summary129S/SvEv-Apctm1Rak/+ Mlh3tm1Lpkn Pms2tm1Lisk

Strain Name

129S/SvEv-Apctm1Rak/+ Mlh3tm1Lpkn Pms2tm1Lisk

Strain Type(s)

targeted mutation (knockout)

Strain Synonym(s)

Mlh3-/-;Pms2-/-;Apc+/1638N  •  Mlh3-/-;Pms2-/-;Apc1638N  •  MPA

Description

Compound mutant mice. This cohort was generated in crosses with other mutant mice and is on a predominantly 129S/SvEv genetic background which also contained at least some 129P2/OlaHsd and some 129S2/SvPas.

Strain Genetics

Apctm1Rak / Apc+

Models

6 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Gastrointestinal tract adenocarcinoma Gastrointestinal tract

observed

References: Chen PC, PLoS Genet 2008 Jun;4(6):e1000092

Gastrointestinal tract adenoma Gastrointestinal tract

observed

References: Chen PC, PLoS Genet 2008 Jun;4(6):e1000092

Gastrointestinal tract tumor Gastrointestinal tract

100

References: Chen PC, PLoS Genet 2008 Jun;4(6):e1000092

1 cytogenetic image(s)

Intestine - Small Intestine - Duodenum adenoma Intestine - Small Intestine - Duodenum

observed

References: Chen PC, PLoS Genet 2008 Jun;4(6):e1000092

1 pathology image(s)

Intestine - Small Intestine - Jejunum adenocarcinoma Intestine - Small Intestine - Jejunum

observed

References: Chen PC, PLoS Genet 2008 Jun;4(6):e1000092

1 pathology image(s)

(Unspecified organ) tumor (Unspecified organ)

100

References: Chen PC, PLoS Genet 2008 Jun;4(6):e1000092