Strain Summary129S/SvEv-Apctm1Rak/+ Mlh3tm1Lpkn

Strain Name

129S/SvEv-Apctm1Rak/+ Mlh3tm1Lpkn

Strain Type(s)

targeted mutation (knockout)

Strain Synonym(s)

MA  •  Mlh3-/-;Apc+/1638N  •  Mlh3-/-;Apc1638N

Description

Compound mutant mice. This cohort was generated in crosses with other mutant mice and is on a predominantly 129S/SvEv genetic background which also contained at least some 129P2/OlaHsd and likely some 129S2/SvPas.

Strain Genetics

Apctm1Rak / Apc+

Models

4 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Gastrointestinal tract adenocarcinoma Gastrointestinal tract

observed

References: Chen PC, PLoS Genet 2008 Jun;4(6):e1000092

Gastrointestinal tract adenoma Gastrointestinal tract

observed

References: Chen PC, PLoS Genet 2008 Jun;4(6):e1000092

Gastrointestinal tract tumor Gastrointestinal tract

100

References: Chen PC, PLoS Genet 2008 Jun;4(6):e1000092

(Unspecified organ) tumor (Unspecified organ)

100

References: Chen PC, PLoS Genet 2008 Jun;4(6):e1000092