Strain Summary129S/SvEv-Mlh3tm1Lpkn Pms2tm1Lisk

Strain Name

129S/SvEv-Mlh3tm1Lpkn Pms2tm1Lisk

Strain Type(s)

targeted mutation (knockout)

Strain Synonym(s)

129 Sv/Ev Mlh3-/-;Pms2-/-  •  Mlh3-/-;Pms2-/-

Description

Double homozygous mice. The genetic background was reported as "129 Sv/Ev" (substrain not specified) and also contained some 129S2/SvPas.

Models

4 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Gastrointestinal tract tumor Gastrointestinal tract

42

References: Chen PC, Cancer Res 2005 Oct 1;65(19):8662-70

Intestine - Large Intestine - Colon adenocarcinoma Intestine - Large Intestine - Colon

observed

References: Chen PC, Cancer Res 2005 Oct 1;65(19):8662-70

Leukocyte lymphoma Leukocyte

58

References: Chen PC, Cancer Res 2005 Oct 1;65(19):8662-70

(Unspecified organ) tumor (Unspecified organ)

84

References: Chen PC, Cancer Res 2005 Oct 1;65(19):8662-70