Strain SummaryFVB;129P2-Ptentm1Mro Tg(KLK3-cre)D4Trp

Strain Name

FVB;129P2-Ptentm1Mro Tg(KLK3-cre)D4Trp

Strain Type(s)

targeted mutation (conditional)  •  transgenic

Strain Synonym(s)

PSA-Cre;Pten-loxP/LoxP

Description

Mice were homozygous for the Ptentm1Mro mutation and carried the Tg(KLK3-cre)D4Trp transgene. The genetic background was a mixture of FVB and 129P2/Ola.

Strain Genetics

Tg(KLK3-cre)D4Trp

Models

2 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Adrenal gland - Medulla pheochromocytoma Adrenal gland - Medulla

30 - 100

References: Korpershoek E, J Pathol 2009 Mar;217(4):597-604

Sites of Metastasis: Lung

Prostate gland tumor Prostate gland

observed

References: Korpershoek E, J Pathol 2009 Mar;217(4):597-604