Strain SummaryB6;129-Dclre1ctm1Fwa Trp53tm1Brd

Strain Name

B6;129-Dclre1ctm1Fwa Trp53tm1Brd

Strain Type(s)

targeted mutation (knockout)

Strain Synonym(s)

AP  •  ArtΔ/Δ Trp53Δ/Δ  •  ArtN/NTrp53N/N

Description

Double homozygous mice. The genetic background of these mice was a mixture of C57BL/6 and "129/Sv" (including at least 129S6/SvEvTac and 129S7/SvEvBrd-Hprt1+).

Models

1 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Leukocyte - Lymphocyte - Pro-B-lymphocyte lymphoma Leukocyte - Lymphocyte - Pro-B-lymphocyte

very high - 100

References: Woo Y, Oncogene 2007 Sep 6;26(41):6010-20   ⋅   Wright SM, Cancer Res 2009 May 15;69(10):4454-60

4 cytogenetic image(s)