Strain Summary129S-Trp53tm1Glo/+

Strain Name

129S-Trp53tm1Glo/+

Strain Type(s)

targeted mutation (knock-in)

Strain Synonym(s)

p53R172HΔg/+  •  p53R172HΔg/+

Description

Heterozygotes. The genetic background of these mice was stated to be greater than 90% 129/Sv. The other strains involved in this background were not specified.

Strain Genetics

Trp53tm1Glo / Trp53+

Models

13 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Bone osteosarcoma Bone

35

References: Zheng S, Oncogene 2007 Oct 18;26(48):6896-904

Connective tissue - Fibroblast fibrosarcoma Connective tissue - Fibroblast

0

References: Zheng S, Oncogene 2007 Oct 18;26(48):6896-904

Intestine - Large Intestine - Rectum adenocarcinoma - mucinous Intestine - Large Intestine - Rectum

0

References: Zheng S, Oncogene 2007 Oct 18;26(48):6896-904

Leukocyte lymphoma Leukocyte

35

References: Zheng S, Oncogene 2007 Oct 18;26(48):6896-904

Sites of Metastasis: Lung

Lung adenocarcinoma Lung

17

References: Zheng S, Oncogene 2007 Oct 18;26(48):6896-904

Sites of Metastasis: (Unspecified organ) , not Adrenal gland , not Eye , not Kidney , not Lymph node - Mesenteric , not Mammary gland , not Muscle - Striated - Skeletal - Diaphragm , not Pancreas , not Pleura - Parietal , Body wall , Heart , Liver , Lymph node - Mediastinal

Lung adenoma Lung

4.3

References: Zheng S, Oncogene 2007 Oct 18;26(48):6896-904

Melanocyte melanoma Melanocyte

0

References: Zheng S, Oncogene 2007 Oct 18;26(48):6896-904

Mesodermal cell/mesoblast sarcoma - unclassified Mesodermal cell/mesoblast

13

References: Zheng S, Oncogene 2007 Oct 18;26(48):6896-904

Mesothelium mesothelioma Pleura - Parietal

0

References: Zheng S, Oncogene 2007 Oct 18;26(48):6896-904

Pancreas carcinoma Pancreas

0

References: Zheng S, Oncogene 2007 Oct 18;26(48):6896-904

(Unspecified organ) angiosarcoma (Unspecified organ)

0

References: Zheng S, Oncogene 2007 Oct 18;26(48):6896-904

(Unspecified organ) papilloma (Unspecified organ)

0

References: Zheng S, Oncogene 2007 Oct 18;26(48):6896-904

(Unspecified organ) squamous cell carcinoma (Unspecified organ)

22

References: Zheng S, Oncogene 2007 Oct 18;26(48):6896-904