Strain SummaryFVB;129P2-Cdkn2atm2Brn/+ Nf2tm2Gth

Strain Name

FVB;129P2-Cdkn2atm2Brn/+ Nf2tm2Gth

Strain Type(s)

targeted mutation (conditional)

Strain Synonym(s)

Nf2f/f Ink4a/Arff/+

Description

Mice were heterozygous for the Cdkn2atm2Brn and homozygous for the Nf2tm2Gth mutations. The genetic background of these mice was a mixture of FVB/N and 129P2/OlaHsd.

Strain Genetics

Cdkn2atm2Brn / Cdkn2a+

Models

14 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Leukocyte - Monocyte leukemia - myelocytic Leukocyte - Monocyte Adenovirus carrying cre recombinase

15.38

References: Jongsma J, Cancer Cell 2008 Mar;13(3):261-71

Leukocyte lymphoma Leukocyte Adenovirus carrying cre recombinase

0

References: Jongsma J, Cancer Cell 2008 Mar;13(3):261-71

Liver - Bile duct cholangiocarcinoma Liver - Bile duct Adenovirus carrying cre recombinase

observed

References: Jongsma J, Cancer Cell 2008 Mar;13(3):261-71

Liver - Oval cell hyperplasia Liver - Oval cell Adenovirus carrying cre recombinase

observed

References: Jongsma J, Cancer Cell 2008 Mar;13(3):261-71

Liver hepatoma Liver Adenovirus carrying cre recombinase

observed

References: Jongsma J, Cancer Cell 2008 Mar;13(3):261-71

Mesothelium mesothelioma - malignant Thoracic cavity Adenovirus carrying cre recombinase

100

References: Jongsma J, Cancer Cell 2008 Mar;13(3):261-71

Mesothelium mesothelioma - malignant - biphasic Thoracic cavity Adenovirus carrying cre recombinase

17.31

References: Jongsma J, Cancer Cell 2008 Mar;13(3):261-71

Mesothelium mesothelioma - malignant - epithelial Thoracic cavity Adenovirus carrying cre recombinase

7.69

References: Jongsma J, Cancer Cell 2008 Mar;13(3):261-71

Mesothelium mesothelioma - malignant - sarcomatoid Thoracic cavity Adenovirus carrying cre recombinase

9.62

References: Jongsma J, Cancer Cell 2008 Mar;13(3):261-71

Muscle - Smooth leiomyoma Uterus Adenovirus carrying cre recombinase

15.38

References: Jongsma J, Cancer Cell 2008 Mar;13(3):261-71

Muscle - Striated - Skeletal rhabdomyosarcoma Thoracic cavity Adenovirus carrying cre recombinase

0

References: Jongsma J, Cancer Cell 2008 Mar;13(3):261-71

PNS - Schwann cell schwannoma Thoracic cavity Adenovirus carrying cre recombinase

0

References: Jongsma J, Cancer Cell 2008 Mar;13(3):261-71

Thoracic cavity tumor Thoracic cavity Adenovirus carrying cre recombinase

34.62

References: Jongsma J, Cancer Cell 2008 Mar;13(3):261-71

(Unspecified organ) tumor (Unspecified organ) Adenovirus carrying cre recombinase

19.23

References: Jongsma J, Cancer Cell 2008 Mar;13(3):261-71