Strain Summary[not specified]-Cdkn2ctm1Bbd Tg(Nes-cre)1Kln Trp53tm1Brn/Trp53tm1Tyj

Strain Name

[not specified]-Cdkn2ctm1Bbd Tg(Nes-cre)1Kln Trp53tm1Brn/Trp53tm1Tyj

Strain Type(s)

targeted mutation (conditional)  •  targeted mutation (knockout)  •  transgenic

Strain Synonym(s)

Ink4c-/-, p53-/FL, Nestin-Cre


Mice were Cdkn2ctm1Bbd homozygotes, had Trp53 KO and floxed alleles, and were transgenic. The genetic background of these mice was not specified but included at least 129P2/OlaHsd, 129S1/Sv, 129S2/SvPas, C57BL/6, and SJL.

Strain Genetics

Trp53tm1Brn / Trp53tm1Tyj


1 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
CNS - Brain - Cerebellum medulloblastoma CNS - Brain - Cerebellum gamma-radiation


References: Uziel T, Genes Dev 2005 Nov 15;19(22):2656-67