Mouse Tumor Biology Database (MTB)
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Last Database Update
2019-12-01
MTB 3.0
 
HelpHelp and Documentation Strain Tumor Overview
Collapsed View
 
Strain
B6;129-Trp53tm1Brd
Strain Synonyms p53-/-  •  p53 null  •  p53 single null  •  p53 SN
Strain Note: Homozygous mice. The genetic background of these mice was a mixture of C57BL/6 and 129/Sv (substrain(s) not specified but included at least 129S7/SvEvBrd-Hprt1+).
Strain Tumor Overview Expanded View
Tumors 24 unique tumor types displayed.

A tumor group is a set of tumors that share the same tumor name, organ(s) affected, and treatment type.

Tumor Name Organ(s) Affected Treatment Type Number of
Tumor Group Records
Frequency Range
Adrenal gland - Medulla hyperplasia Adrenal gland - Medulla None (spontaneous) 1 0
Adrenal gland - Medulla pheochromocytoma Adrenal gland - Medulla None (spontaneous) 1 0
Blood vessel hemangiosarcoma Blood vessel None (spontaneous) 1 0
Bone osteosarcoma Bone None (spontaneous) 1 0
Connective tissue - Fibroblast fibrosarcoma Connective tissue - Fibroblast None (spontaneous) 1 0
Intestine - Large Intestine - Colon adenocarcinoma Intestine - Large Intestine - Colon None (spontaneous) 1 0
Intestine - Large Intestine - Colon adenoma Intestine - Large Intestine - Colon None (spontaneous) 1 0
Intestine - Large Intestine - Colon hyperplasia Intestine - Large Intestine - Colon None (spontaneous) 1 0
Leukocyte lymphoma Leukocyte None (spontaneous) 20 44
Liver hepatocellular carcinoma Liver None (spontaneous) 1 0
Mesodermal cell/mesoblast sarcoma Mesodermal cell/mesoblast None (spontaneous) 1 37.5
Mesodermal cell/mesoblast sarcoma - undifferentiated Mesodermal cell/mesoblast None (spontaneous) 1 37.5
Muscle - Smooth leiomyosarcoma Muscle - Smooth None (spontaneous) 1 0
Pituitary gland adenocarcinoma Pituitary gland None (spontaneous) 1 0
Pituitary gland adenoma Pituitary gland None (spontaneous) 1 0
Pituitary gland hyperplasia Pituitary gland None (spontaneous) 1 0
Stomach adenoma Stomach None (spontaneous) 1 0
Stomach squamous cell papilloma Stomach None (spontaneous) 1 0
Testis - Leydig cell (Interstitial cell) hyperplasia Testis - Leydig cell (Interstitial cell) None (spontaneous) 1 18
Testis adenoma Testis None (spontaneous) 1 0
Testis choriocarcinoma Testis None (spontaneous) 1 0
Thyroid gland - Medulla - C cell adenoma Thyroid gland - Medulla - C cell None (spontaneous) 1 0
Thyroid gland - Medulla - C cell hyperplasia Thyroid gland - Medulla - C cell None (spontaneous) 1 0
(Unspecified organ) tumor (Unspecified organ) None (spontaneous) 1 very high